Detailed information NTG1119819

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: EL086_RS04945
• Genome accession: NZ_LR134274
• Coordinates: 1001117..1001998 (+)
• Length: 293 a.a.
• NCBI ID: WP_038675882.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC8618
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 996117..1006998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL086_RS04920 (NCTC8618_03406)	-	996650..998071 (+)	1422	WP_038675879.1	DUF4832 domain-containing protein	-
EL086_RS04925 (NCTC8618_03407)	galE	998086..999099 (+)	1014	WP_021144269.1	UDP-glucose 4-epimerase GalE	-
EL086_RS04930 (NCTC8618_03408)	-	999291..999527 (+)	237	WP_037603973.1	DUF1146 family protein	-
EL086_RS04935 (NCTC8618_03409)	murA	999595..1000866 (+)	1272	WP_038675881.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL086_RS04940 (NCTC8618_03410)	-	1000868..1001056 (+)	189	WP_013990684.1	DNA-directed RNA polymerase subunit beta	-
EL086_RS04945 (NCTC8618_03411)	endA	1001117..1001998 (+)	882	WP_038675882.1	DNA/RNA non-specific endonuclease	Machinery gene
EL086_RS04950 (NCTC8618_03412)	-	1002074..1002724 (-)	651	WP_002886253.1	amino acid ABC transporter permease	-
EL086_RS04955 (NCTC8618_03413)	-	1002736..1003434 (-)	699	WP_002886251.1	amino acid ABC transporter permease	-
EL086_RS04960 (NCTC8618_03414)	-	1003452..1004285 (-)	834	WP_060775855.1	transporter substrate-binding domain-containing protein	-
EL086_RS04965 (NCTC8618_03415)	-	1004297..1005064 (-)	768	WP_060775856.1	amino acid ABC transporter ATP-binding protein	-
EL086_RS04970 (NCTC8618_03416)	-	1005250..1005900 (-)	651	WP_002886253.1	amino acid ABC transporter permease	-
EL086_RS04975 (NCTC8618_03417)	-	1005912..1006610 (-)	699	WP_002886251.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31566.19 Da
• Isoelectric Point: 10.1795

>NTDB_id=1119819 EL086_RS04945 WP_038675882.1 1001117..1001998(+) (endA) [Streptococcus salivarius strain NCTC8618]
MAKRKTSLTNKQKRQLVSLLIAVLIAVLGYVGTSNKLSPNNPIKQVASLVSGKSNNYVKSNGSTSGQSTPQEQLAETVMT
SSVKSQLGNAIEWNGAGAYIVNGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVHNLSGEYSHAVDRGHLLGYALVGGLKGFDASTSNPENIAVQTAWANQANSETSTGQNYYESLVRKAQDKNKRVR
YRVTLIYEGDNLIPSGSHLEAKSADGSLEFNVFVPNVQQGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1119819 EL086_RS04945 WP_038675882.1 1001117..1001998(+) (endA) [Streptococcus salivarius strain NCTC8618]
ATGGCAAAAAGAAAGACATCTTTAACAAATAAACAGAAACGTCAGCTAGTCTCGTTACTGATAGCGGTTTTGATTGCAGT
TTTAGGTTACGTTGGAACGAGTAATAAGCTCTCACCTAACAATCCAATCAAGCAGGTAGCTAGTCTAGTCTCGGGAAAAT
CCAATAACTACGTCAAATCAAACGGCTCAACAAGTGGGCAGTCTACGCCACAAGAGCAACTCGCAGAGACGGTGATGACC
AGCTCTGTCAAGAGTCAACTAGGAAACGCCATAGAATGGAATGGGGCTGGTGCCTATATTGTTAACGGTAATAAAACCAA
TCTTAATGCTAAGGTATCTAGCCAACCCTACGCTAATAACCAAGTTAAAACGGTTCAAGGACAAACGGTTCCTACAGTTG
CGAATGCCTTGTTAAGTAAAGCGACCAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGCTCAACCTCTTGGACACCA
GCTGGATGGCATCAAGTTCACAATCTTTCAGGAGAGTATAGCCATGCCGTAGACCGAGGCCATTTGTTAGGTTATGCACT
TGTAGGTGGTCTCAAAGGATTTGATGCCTCGACTTCAAATCCAGAAAATATTGCCGTTCAAACTGCTTGGGCTAACCAAG
CTAATAGCGAAACTTCCACAGGCCAAAACTATTATGAAAGCCTGGTACGTAAAGCTCAGGATAAAAATAAACGTGTCCGT
TATCGCGTTACCCTCATTTATGAAGGAGATAACCTGATTCCATCAGGATCACATCTTGAAGCCAAGTCAGCAGATGGCTC
GCTTGAGTTCAACGTCTTCGTTCCAAATGTCCAACAGGGAATTACCCTAGATTATTATTCAGGGAAAGTAACGGTGAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	69.96	86.348	0.604
endA	Streptococcus pneumoniae D39	69.96	86.348	0.604
endA	Streptococcus pneumoniae R6	69.96	86.348	0.604
endA	Streptococcus pneumoniae TIGR4	69.96	86.348	0.604