Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AT689_RS04210 Genome accession   NZ_LN831051
Coordinates   784635..785459 (+) Length   274 a.a.
NCBI ID   WP_001036790.1    Uniprot ID   A0A0B7KWT3
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 779635..790459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS04175 (ERS445053_00811) asnA 779726..780718 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  AT689_RS04180 (ERS445053_00812) rsmD 780783..781322 (+) 540 WP_000706967.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AT689_RS04190 (ERS445053_00813) - 781312..782820 (+) 1509 WP_001280730.1 SepM family pheromone-processing serine protease -
  AT689_RS04195 (ERS445053_00814) - 782878..783108 (+) 231 WP_000250393.1 DUF1146 family protein -
  AT689_RS04200 (ERS445053_00815) murA 783132..784415 (+) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AT689_RS04205 (ERS445053_00816) - 784408..784596 (+) 189 WP_001818955.1 DNA-directed RNA polymerase subunit beta -
  AT689_RS04210 (ERS445053_00817) endA 784635..785459 (+) 825 WP_001036790.1 DNA-entry nuclease EndA Machinery gene
  AT689_RS04215 (ERS445053_00818) - 785750..787081 (+) 1332 WP_000390039.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29949.69 Da        Isoelectric Point: 10.1700

>NTDB_id=1114376 AT689_RS04210 WP_001036790.1 784635..785459(+) (endA) [Streptococcus pneumoniae strain NCTC7465]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1114376 AT689_RS04210 WP_001036790.1 784635..785459(+) (endA) [Streptococcus pneumoniae strain NCTC7465]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGTAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTATAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KWT3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment