Detailed information NTG1111686

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: HMPREF9319_RS03160
• Genome accession: NZ_GL397128
• Coordinates: 643647..644513 (+)
• Length: 288 a.a.
• NCBI ID: WP_003064105.1
• Uniprot ID: E0PCS6
• Organism: Streptococcus equinus ATCC 700338
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 638647..649513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9319_RS03130 (HMPREF9319_0643)	-	638732..639610 (+)	879	WP_003064089.1	F0F1 ATP synthase subunit gamma	-
HMPREF9319_RS03135 (HMPREF9319_0644)	atpD	639677..641083 (+)	1407	WP_003064092.1	F0F1 ATP synthase subunit beta	-
HMPREF9319_RS03140 (HMPREF9319_0645)	-	641096..641512 (+)	417	WP_003064095.1	F0F1 ATP synthase subunit epsilon	-
HMPREF9319_RS03145 (HMPREF9319_0646)	-	641768..642004 (+)	237	WP_003064099.1	DUF1146 family protein	-
HMPREF9319_RS03150 (HMPREF9319_0647)	murA	642067..643341 (+)	1275	WP_041974287.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HMPREF9319_RS03155 (HMPREF9319_0648)	-	643344..643532 (+)	189	WP_003064103.1	DNA-directed RNA polymerase subunit beta	-
HMPREF9319_RS03160 (HMPREF9319_0649)	endA	643647..644513 (+)	867	WP_003064105.1	DNA/RNA non-specific endonuclease	Machinery gene
HMPREF9319_RS03165 (HMPREF9319_0650)	pheS	644800..645843 (+)	1044	WP_013642932.1	phenylalanine--tRNA ligase subunit alpha	-
HMPREF9319_RS03170	-	645879..646371 (+)	493	Protein_633	GNAT family N-acetyltransferase	-
HMPREF9319_RS03175 (HMPREF9319_0654)	pheT	646442..648847 (+)	2406	WP_003064115.1	phenylalanine--tRNA ligase subunit beta	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 30866.05 Da
• Isoelectric Point: 6.4909

>NTDB_id=1111686 HMPREF9319_RS03160 WP_003064105.1 643647..644513(+) (endA) [Streptococcus equinus ATCC 700338]
MAKKSKLSKQIKSLLSLVILLVGIGTGWVTISDSNDPLNQVVSLITGDSSSEITSNQSGSDSATPTQALAETVLTDSVKE
QLGTNIEWNGAGAYIINNNQTSLNAKVSSQPYANNKTKTVQGQTVPTVANALLSKSTRQYKSREETGNGSTSWKPAGWHQ
VQDLSGTYSHAVDRGHLLGYALVGGLKGFDASTSNPDNVATQTAWANEANSESSTGQNYYECLVRKALDQNKRVRYRVTL
IYDGDNLLASGTHLEAKSSDGSLEFNVFIPNVQSGLTFDYYSGQVSVN

Nucleotide

• Length: 867 bp

>NTDB_id=1111686 HMPREF9319_RS03160 WP_003064105.1 643647..644513(+) (endA) [Streptococcus equinus ATCC 700338]
ATGGCAAAGAAATCAAAATTGTCTAAACAGATAAAATCCCTGCTGTCTTTGGTGATTTTGTTAGTTGGGATTGGTACTGG
TTGGGTGACGATATCAGATTCGAACGACCCGCTCAATCAAGTCGTTTCGTTAATTACTGGTGATTCCTCTTCTGAAATAA
CATCAAATCAATCGGGTTCTGATTCAGCAACGCCAACACAAGCTTTAGCAGAGACGGTATTAACAGATAGTGTCAAAGAG
CAGTTGGGAACAAATATAGAATGGAATGGTGCGGGAGCCTATATTATCAATAATAATCAAACCTCTCTAAATGCAAAAGT
TTCAAGTCAACCTTACGCCAACAACAAAACGAAAACGGTGCAAGGTCAGACCGTTCCAACGGTTGCTAATGCTTTGCTAA
GTAAGTCAACTCGTCAATACAAAAGTCGTGAGGAGACTGGAAATGGCTCAACGTCTTGGAAGCCAGCTGGTTGGCATCAA
GTTCAAGACCTTTCAGGGACTTATAGCCATGCGGTAGATCGTGGTCATTTGCTTGGCTATGCTTTGGTTGGTGGTCTAAA
AGGCTTTGATGCGTCAACAAGCAATCCTGACAATGTGGCAACACAGACTGCCTGGGCAAACGAGGCAAATTCGGAAAGTT
CAACTGGTCAAAATTACTATGAATGCCTTGTCCGCAAAGCTCTTGACCAAAATAAACGAGTTCGTTACCGTGTTACCTTG
ATTTACGATGGAGACAATCTTTTAGCAAGTGGCACGCATTTGGAAGCCAAATCATCCGATGGTAGTCTAGAATTTAACGT
CTTTATTCCAAATGTGCAAAGCGGACTAACATTTGATTATTATTCAGGTCAAGTTAGTGTGAATTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (96-247)

3D structure

• AlphaFold DB: E0PCS6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.726	86.111	0.566
endA	Streptococcus pneumoniae D39	65.726	86.111	0.566
endA	Streptococcus pneumoniae R6	65.726	86.111	0.566
endA	Streptococcus pneumoniae TIGR4	65.726	86.111	0.566