Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | ACM3H0_RS06525 | Genome accession | NZ_CP180685 |
| Coordinates | 1214843..1215817 (-) | Length | 324 a.a. |
| NCBI ID | WP_001008570.1 | Uniprot ID | A0AAW6XQQ3 |
| Organism | Streptococcus agalactiae strain M14 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1170426..1216106 | 1214843..1215817 | within | 0 |
Gene organization within MGE regions
Location: 1170426..1216106
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACM3H0_RS06275 (ACM3H0_06275) | - | 1170547..1170837 (-) | 291 | WP_000158581.1 | DUF5962 family protein | - |
| ACM3H0_RS06280 (ACM3H0_06280) | - | 1170848..1171702 (-) | 855 | WP_000005759.1 | phage replisome organizer N-terminal domain-containing protein | - |
| ACM3H0_RS06285 (ACM3H0_06285) | - | 1171714..1171998 (-) | 285 | WP_001287945.1 | hypothetical protein | - |
| ACM3H0_RS06290 (ACM3H0_06290) | - | 1172145..1172663 (+) | 519 | WP_000181342.1 | helix-turn-helix domain-containing protein | - |
| ACM3H0_RS06295 (ACM3H0_06295) | - | 1172718..1173872 (+) | 1155 | WP_000110711.1 | site-specific integrase | - |
| ACM3H0_RS06300 (ACM3H0_06300) | rpsI | 1174018..1174410 (-) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| ACM3H0_RS06305 (ACM3H0_06305) | rplM | 1174431..1174877 (-) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| ACM3H0_RS06310 (ACM3H0_06310) | - | 1175178..1176344 (+) | 1167 | WP_000160598.1 | IS30-like element ISSag9 family transposase | - |
| ACM3H0_RS06315 (ACM3H0_06315) | - | 1176662..1176781 (-) | 120 | Protein_1169 | helix-turn-helix transcriptional regulator | - |
| ACM3H0_RS06320 (ACM3H0_06320) | - | 1177319..1178179 (-) | 861 | WP_000143135.1 | DegV family protein | - |
| ACM3H0_RS06325 (ACM3H0_06325) | - | 1178272..1178790 (-) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| ACM3H0_RS06330 (ACM3H0_06330) | rlmB | 1178787..1179542 (-) | 756 | WP_416055425.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| ACM3H0_RS06335 (ACM3H0_06335) | - | 1179645..1180031 (-) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| ACM3H0_RS06340 (ACM3H0_06340) | cysS | 1180024..1181367 (-) | 1344 | WP_416055426.1 | cysteine--tRNA ligase | - |
| ACM3H0_RS06345 (ACM3H0_06345) | - | 1181364..1181546 (-) | 183 | WP_000656477.1 | hypothetical protein | - |
| ACM3H0_RS06350 (ACM3H0_06350) | cysE | 1181556..1182140 (-) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| ACM3H0_RS06355 (ACM3H0_06355) | - | 1182149..1182901 (-) | 753 | WP_000204780.1 | SseB family protein | - |
| ACM3H0_RS06360 (ACM3H0_06360) | pnp | 1182903..1185032 (-) | 2130 | WP_192801119.1 | polyribonucleotide nucleotidyltransferase | - |
| ACM3H0_RS06365 (ACM3H0_06365) | rpsO | 1185413..1185682 (-) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| ACM3H0_RS06370 (ACM3H0_06370) | - | 1185770..1187029 (-) | 1260 | WP_001203074.1 | ferric reductase-like transmembrane domain-containing protein | - |
| ACM3H0_RS06375 (ACM3H0_06375) | - | 1187138..1188067 (-) | 930 | WP_001203828.1 | transketolase family protein | - |
| ACM3H0_RS06380 (ACM3H0_06380) | - | 1188064..1188921 (-) | 858 | WP_000203492.1 | transketolase | - |
| ACM3H0_RS06385 (ACM3H0_06385) | - | 1188924..1190279 (-) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| ACM3H0_RS06390 (ACM3H0_06390) | - | 1190292..1190576 (-) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| ACM3H0_RS06395 (ACM3H0_06395) | - | 1190579..1192615 (-) | 2037 | WP_000228178.1 | BglG family transcription antiterminator | - |
| ACM3H0_RS06400 (ACM3H0_06400) | treC | 1192835..1194460 (-) | 1626 | WP_000151014.1 | alpha,alpha-phosphotrehalase | - |
| ACM3H0_RS06405 (ACM3H0_06405) | treP | 1194682..1196712 (-) | 2031 | WP_000434610.1 | PTS system trehalose-specific EIIBC component | - |
| ACM3H0_RS06410 (ACM3H0_06410) | - | 1196994..1197620 (-) | 627 | WP_000171304.1 | ABC transporter ATP-binding protein | - |
| ACM3H0_RS06415 (ACM3H0_06415) | - | 1197604..1198407 (-) | 804 | WP_000140979.1 | ABC transporter ATP-binding protein | - |
| ACM3H0_RS06420 (ACM3H0_06420) | - | 1198419..1199240 (-) | 822 | WP_000603397.1 | ABC transporter permease | - |
| ACM3H0_RS06425 (ACM3H0_06425) | - | 1199237..1200214 (-) | 978 | WP_000680644.1 | ABC transporter permease | - |
| ACM3H0_RS06430 (ACM3H0_06430) | - | 1200327..1201955 (-) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| ACM3H0_RS06435 (ACM3H0_06435) | lrgB | 1202198..1202926 (-) | 729 | WP_000421727.1 | antiholin-like protein LrgB | - |
| ACM3H0_RS06440 (ACM3H0_06440) | - | 1202928..1203383 (-) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| ACM3H0_RS06445 (ACM3H0_06445) | - | 1203553..1204293 (-) | 741 | WP_000697630.1 | LytR/AlgR family response regulator transcription factor | - |
| ACM3H0_RS06450 (ACM3H0_06450) | - | 1204274..1206019 (-) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| ACM3H0_RS06455 (ACM3H0_06455) | - | 1206046..1206690 (-) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| ACM3H0_RS06460 (ACM3H0_06460) | ssbA | 1206813..1207208 (-) | 396 | WP_000282450.1 | single-stranded DNA-binding protein | Machinery gene |
| ACM3H0_RS06465 (ACM3H0_06465) | - | 1207289..1208005 (+) | 717 | WP_000186183.1 | class I SAM-dependent methyltransferase | - |
| ACM3H0_RS06470 (ACM3H0_06470) | ytpR | 1208059..1208685 (-) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| ACM3H0_RS06475 (ACM3H0_06475) | - | 1208718..1209041 (-) | 324 | WP_000601792.1 | thioredoxin family protein | - |
| ACM3H0_RS06480 (ACM3H0_06480) | - | 1209038..1209322 (-) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| ACM3H0_RS06485 (ACM3H0_06485) | - | 1209483..1209722 (+) | 240 | WP_000660181.1 | hypothetical protein | - |
| ACM3H0_RS06490 (ACM3H0_06490) | pepA | 1209907..1210974 (+) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| ACM3H0_RS06495 (ACM3H0_06495) | proC | 1211044..1211814 (+) | 771 | WP_001867096.1 | pyrroline-5-carboxylate reductase | - |
| ACM3H0_RS06500 (ACM3H0_06500) | - | 1211835..1212500 (-) | 666 | WP_000008111.1 | CPBP family intramembrane glutamic endopeptidase | - |
| ACM3H0_RS06505 (ACM3H0_06505) | - | 1212569..1213024 (-) | 456 | WP_000905674.1 | hypothetical protein | - |
| ACM3H0_RS06510 (ACM3H0_06510) | - | 1213065..1213202 (-) | 138 | WP_001867090.1 | hypothetical protein | - |
| ACM3H0_RS06515 (ACM3H0_06515) | - | 1213261..1213467 (-) | 207 | WP_000798242.1 | helix-turn-helix transcriptional regulator | - |
| ACM3H0_RS06520 (ACM3H0_06520) | - | 1213618..1214811 (-) | 1194 | WP_000047535.1 | acetate kinase | - |
| ACM3H0_RS06525 (ACM3H0_06525) | comYH | 1214843..1215817 (-) | 975 | WP_001008570.1 | class I SAM-dependent methyltransferase | Machinery gene |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37100.99 Da Isoelectric Point: 4.4041
>NTDB_id=1097417 ACM3H0_RS06525 WP_001008570.1 1214843..1215817(-) (comYH) [Streptococcus agalactiae strain M14]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
Nucleotide
Download Length: 975 bp
>NTDB_id=1097417 ACM3H0_RS06525 WP_001008570.1 1214843..1215817(-) (comYH) [Streptococcus agalactiae strain M14]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.984 |
97.222 |
0.651 |
| comYH | Streptococcus mutans UA140 |
66.984 |
97.222 |
0.651 |