Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACAM23_RS02815 Genome accession   NZ_AP031394
Coordinates   530394..531131 (+) Length   245 a.a.
NCBI ID   WP_001219136.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P28     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 525394..536131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM23_RS02785 (SPNE16P28_05420) - 526725..527012 (-) 288 WP_000777760.1 hypothetical protein -
  ACAM23_RS02790 (SPNE16P28_05430) - 527022..527432 (-) 411 WP_001278301.1 HIT family protein -
  ACAM23_RS02795 (SPNE16P28_05440) pptA 527500..528231 (+) 732 WP_000889924.1 ABC transporter ATP-binding protein Regulator
  ACAM23_RS02800 (SPNE16P28_05450) - 528228..529277 (+) 1050 WP_000653779.1 ABC transporter permease -
  ACAM23_RS02805 (SPNE16P28_05460) - 529445..529774 (-) 330 WP_000132583.1 hypothetical protein -
  ACAM23_RS02810 (SPNE16P28_05470) - 530051..530389 (+) 339 WP_000682136.1 LytTR family DNA-binding domain-containing protein -
  ACAM23_RS02815 (SPNE16P28_05480) comE/blpR 530394..531131 (+) 738 WP_001219136.1 LytTR family DNA-binding domain-containing protein Regulator
  ACAM23_RS02820 (SPNE16P28_05490) - 531145..532485 (+) 1341 WP_001017643.1 sensor histidine kinase -
  ACAM23_RS02825 (SPNE16P28_05500) blpC 532556..532684 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  ACAM23_RS02830 (SPNE16P28_05510) - 532741..534102 (-) 1362 Protein_557 bacteriocin secretion accessory protein -
  ACAM23_RS02835 (SPNE16P28_05530) comA/nlmT 534113..535789 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28782.99 Da        Isoelectric Point: 6.4147

>NTDB_id=108949 ACAM23_RS02815 WP_001219136.1 530394..531131(+) (comE/blpR) [Streptococcus pneumoniae strain 16P28]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INKLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=108949 ACAM23_RS02815 WP_001219136.1 530394..531131(+) (comE/blpR) [Streptococcus pneumoniae strain 16P28]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCCCGTTATAAGGTCAGGGAAGTGTCTGAGGCC
ATCAATAAATTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.017

98.776

0.376

Multiple sequence alignment