Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ACLIMC_RS18840 Genome accession   NZ_CP177035
Coordinates   3665252..3666031 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus thuringiensis strain MPB08     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3630930..3704855 3665252..3666031 within 0


Gene organization within MGE regions


Location: 3630930..3704855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLIMC_RS18690 (ACLIMC_18690) - 3631273..3632943 (-) 1671 WP_000823085.1 ribonuclease J -
  ACLIMC_RS18695 (ACLIMC_18695) dapA 3633709..3634587 (-) 879 WP_263696149.1 4-hydroxy-tetrahydrodipicolinate synthase -
  ACLIMC_RS18700 (ACLIMC_18700) dapG 3634599..3635831 (-) 1233 WP_000692470.1 aspartate kinase -
  ACLIMC_RS18705 (ACLIMC_18705) asd 3635855..3636901 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  ACLIMC_RS18710 (ACLIMC_18710) dpaB 3637052..3637651 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  ACLIMC_RS18715 (ACLIMC_18715) dpaA 3637648..3638550 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  ACLIMC_RS18720 (ACLIMC_18720) - 3638825..3639076 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  ACLIMC_RS18725 (ACLIMC_18725) - 3639203..3640444 (-) 1242 WP_000592993.1 M16 family metallopeptidase -
  ACLIMC_RS18730 (ACLIMC_18730) - 3640531..3641430 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  ACLIMC_RS18735 (ACLIMC_18735) pnp 3641582..3643720 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  ACLIMC_RS18740 (ACLIMC_18740) rpsO 3643881..3644150 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  ACLIMC_RS18745 (ACLIMC_18745) ribF 3644251..3645222 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  ACLIMC_RS18750 (ACLIMC_18750) truB 3645266..3646189 (-) 924 WP_000399337.1 tRNA pseudouridine(55) synthase TruB -
  ACLIMC_RS18755 (ACLIMC_18755) rbfA 3646276..3646632 (-) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  ACLIMC_RS18760 (ACLIMC_18760) - 3646648..3646929 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  ACLIMC_RS18765 (ACLIMC_18765) infB 3646926..3648986 (-) 2061 WP_000036341.1 translation initiation factor IF-2 -
  ACLIMC_RS18770 (ACLIMC_18770) - 3648991..3649302 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  ACLIMC_RS18775 (ACLIMC_18775) rnpM 3649303..3649575 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  ACLIMC_RS18780 (ACLIMC_18780) nusA 3649587..3650693 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  ACLIMC_RS18785 (ACLIMC_18785) rimP 3650711..3651181 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  ACLIMC_RS18790 (ACLIMC_18790) - 3651514..3655815 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  ACLIMC_RS18795 (ACLIMC_18795) - 3655940..3657640 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  ACLIMC_RS18800 (ACLIMC_18800) rseP 3657750..3659006 (-) 1257 WP_001090229.1 RIP metalloprotease RseP -
  ACLIMC_RS18805 (ACLIMC_18805) dxr 3659023..3660165 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  ACLIMC_RS18810 (ACLIMC_18810) cdsA 3660189..3660980 (-) 792 WP_000813583.1 phosphatidate cytidylyltransferase -
  ACLIMC_RS18815 (ACLIMC_18815) uppS 3660998..3661774 (-) 777 WP_000971301.1 isoprenyl transferase -
  ACLIMC_RS18820 (ACLIMC_18820) frr 3661860..3662417 (-) 558 WP_000531503.1 ribosome recycling factor -
  ACLIMC_RS18825 (ACLIMC_18825) pyrH 3662420..3663142 (-) 723 WP_000042663.1 UMP kinase -
  ACLIMC_RS18830 (ACLIMC_18830) tsf 3663209..3664096 (-) 888 WP_001018581.1 translation elongation factor Ts -
  ACLIMC_RS18835 (ACLIMC_18835) rpsB 3664200..3664901 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  ACLIMC_RS18840 (ACLIMC_18840) codY 3665252..3666031 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ACLIMC_RS18845 (ACLIMC_18845) hslU 3666109..3667500 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  ACLIMC_RS18850 (ACLIMC_18850) hslV 3667523..3668065 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  ACLIMC_RS18855 (ACLIMC_18855) xerC 3668108..3669007 (-) 900 WP_001101227.1 tyrosine recombinase XerC -
  ACLIMC_RS18860 (ACLIMC_18860) trmFO 3669073..3670377 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  ACLIMC_RS18865 (ACLIMC_18865) topA 3670428..3672506 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  ACLIMC_RS18870 (ACLIMC_18870) dprA 3672651..3673520 (-) 870 WP_000818033.1 DNA-processing protein DprA -
  ACLIMC_RS18875 (ACLIMC_18875) sucD 3673608..3674510 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  ACLIMC_RS18880 (ACLIMC_18880) sucC 3674530..3675690 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  ACLIMC_RS18885 (ACLIMC_18885) rnhB 3675884..3676657 (-) 774 WP_411500932.1 ribonuclease HII -
  ACLIMC_RS18890 (ACLIMC_18890) ylqF 3676709..3677599 (-) 891 WP_000236696.1 ribosome biogenesis GTPase YlqF -
  ACLIMC_RS18895 (ACLIMC_18895) lepB 3677620..3678171 (-) 552 WP_000711857.1 signal peptidase I -
  ACLIMC_RS18900 (ACLIMC_18900) rplS 3678273..3678617 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  ACLIMC_RS18905 (ACLIMC_18905) trmD 3678764..3679498 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  ACLIMC_RS18910 (ACLIMC_18910) rimM 3679498..3680013 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  ACLIMC_RS18915 (ACLIMC_18915) - 3680134..3680361 (-) 228 WP_000737398.1 KH domain-containing protein -
  ACLIMC_RS18920 (ACLIMC_18920) rpsP 3680376..3680648 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  ACLIMC_RS18925 (ACLIMC_18925) ffh 3680749..3682098 (-) 1350 WP_000863458.1 signal recognition particle protein -
  ACLIMC_RS18930 (ACLIMC_18930) - 3682111..3682443 (-) 333 WP_000891062.1 putative DNA-binding protein -
  ACLIMC_RS18935 (ACLIMC_18935) ftsY 3682577..3683566 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  ACLIMC_RS18940 (ACLIMC_18940) smc 3683582..3687151 (-) 3570 WP_000478986.1 chromosome segregation protein SMC -
  ACLIMC_RS18945 (ACLIMC_18945) rncS 3687298..3688035 (-) 738 WP_001146873.1 ribonuclease III -
  ACLIMC_RS18950 (ACLIMC_18950) acpP 3688094..3688327 (-) 234 WP_000786062.1 acyl carrier protein -
  ACLIMC_RS18955 (ACLIMC_18955) fabG 3688397..3689137 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  ACLIMC_RS18960 (ACLIMC_18960) fabD 3689137..3690081 (-) 945 WP_000516948.1 ACP S-malonyltransferase -
  ACLIMC_RS18965 (ACLIMC_18965) plsX 3690096..3691088 (-) 993 WP_411500933.1 phosphate acyltransferase PlsX -
  ACLIMC_RS18970 (ACLIMC_18970) fapR 3691085..3691678 (-) 594 WP_000747352.1 transcription factor FapR -
  ACLIMC_RS18975 (ACLIMC_18975) recG 3691767..3693815 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  ACLIMC_RS18980 (ACLIMC_18980) - 3694105..3695781 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  ACLIMC_RS18985 (ACLIMC_18985) - 3695804..3696166 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  ACLIMC_RS18990 (ACLIMC_18990) rpmB 3696545..3696733 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  ACLIMC_RS18995 (ACLIMC_18995) spoVM 3696807..3696887 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  ACLIMC_RS19000 (ACLIMC_19000) - 3696954..3697634 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  ACLIMC_RS19005 (ACLIMC_19005) rpe 3697734..3698378 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  ACLIMC_RS19010 (ACLIMC_19010) rsgA 3698381..3699262 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  ACLIMC_RS19015 (ACLIMC_19015) prkC 3699531..3701504 (-) 1974 WP_000904757.1 serine/threonine protein kinase PrkC -
  ACLIMC_RS19020 (ACLIMC_19020) - 3701513..3702265 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACLIMC_RS19025 (ACLIMC_19025) rlmN 3702270..3703358 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ACLIMC_RS19030 (ACLIMC_19030) rsmB 3703363..3704697 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=1084995 ACLIMC_RS18840 WP_000421288.1 3665252..3666031(-) (codY) [Bacillus thuringiensis strain MPB08]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=1084995 ACLIMC_RS18840 WP_000421288.1 3665252..3666031(-) (codY) [Bacillus thuringiensis strain MPB08]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATAGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment