Detailed information NTG0107532

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: EX97_RS06315
• Genome accession: NZ_CP007690
• Coordinates: 1273597..1274370 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1268597..1279370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EX97_RS06295 (EX97_06010)	trmFO	1268941..1270248 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
EX97_RS06300 (EX97_06015)	xerC	1270665..1271561 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
EX97_RS06305 (EX97_06020)	hslV	1271558..1272103 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
EX97_RS06310 (EX97_06025)	hslU	1272169..1273572 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
EX97_RS06315 (EX97_06030)	codY	1273597..1274370 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
EX97_RS06320	-	1274421..1274513 (+)	93	WP_001790530.1	hypothetical protein	-
EX97_RS06325 (EX97_06035)	rpsB	1274712..1275479 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
EX97_RS06330	-	1275513..1275626 (+)	114	WP_001789890.1	hypothetical protein	-
EX97_RS06335 (EX97_06040)	tsf	1275661..1276542 (+)	882	WP_000201387.1	translation elongation factor Ts	-
EX97_RS06340 (EX97_06045)	pyrH	1276679..1277401 (+)	723	WP_000057330.1	UMP kinase	-
EX97_RS06345 (EX97_06050)	frr	1277420..1277974 (+)	555	WP_001280006.1	ribosome recycling factor	-
EX97_RS06350 (EX97_06055)	-	1278347..1279117 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=107532 EX97_RS06315 WP_000055337.1 1273597..1274370(+) (codY) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=107532 EX97_RS06315 WP_000055337.1 1273597..1274370(+) (codY) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428