Detailed information NTG0107311

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: EQ80_RS10660
• Genome accession: NZ_CP007672
• Coordinates: 2092591..2093304 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain CA12
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2087591..2098304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQ80_RS15170	-	2088960..2089223 (-)	264	WP_001205732.1	hypothetical protein	-
EQ80_RS10610 (EQ80_010060)	-	2089232..2089492 (-)	261	WP_000291513.1	DUF1108 family protein	-
EQ80_RS10615 (EQ80_010065)	-	2089532..2089792 (-)	261	WP_001549178.1	DUF2482 family protein	-
EQ80_RS10620	-	2089887..2090048 (-)	162	WP_001285960.1	DUF1270 domain-containing protein	-
EQ80_RS10625 (EQ80_010075)	-	2090045..2090365 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
EQ80_RS10630 (EQ80_010080)	-	2090424..2090654 (+)	231	WP_000549548.1	hypothetical protein	-
EQ80_RS15625	-	2090651..2090827 (-)	177	WP_001001356.1	hypothetical protein	-
EQ80_RS10635 (EQ80_010090)	-	2090843..2091595 (-)	753	WP_001148642.1	phage antirepressor KilAC domain-containing protein	-
EQ80_RS10640 (EQ80_010095)	-	2091646..2091975 (+)	330	WP_000180411.1	hypothetical protein	-
EQ80_RS10645 (EQ80_010100)	-	2091964..2092179 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
EQ80_RS10650 (EQ80_010105)	-	2092195..2092458 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
EQ80_RS10655	-	2092455..2092628 (-)	174	WP_001801500.1	hypothetical protein	-
EQ80_RS10660 (EQ80_010110)	irvR	2092591..2093304 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
EQ80_RS10665 (EQ80_010115)	-	2093320..2094252 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
EQ80_RS10670 (EQ80_010120)	-	2094258..2094599 (+)	342	WP_000591749.1	hypothetical protein	-
EQ80_RS10675 (EQ80_010125)	-	2094803..2094985 (+)	183	WP_000705246.1	hypothetical protein	-
EQ80_RS10680 (EQ80_010130)	-	2095063..2095776 (+)	714	WP_001549185.1	type II toxin-antitoxin system PemK/MazF family toxin	-
EQ80_RS10685 (EQ80_010135)	-	2095967..2097004 (+)	1038	WP_000857198.1	tyrosine-type recombinase/integrase	-
EQ80_RS10690 (EQ80_010140)	sph	2097061..2097885 (+)	825	Protein_2030	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=107311 EQ80_RS10660 WP_001031454.1 2092591..2093304(+) (irvR) [Staphylococcus aureus strain CA12]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=107311 EQ80_RS10660 WP_001031454.1 2092591..2093304(+) (irvR) [Staphylococcus aureus strain CA12]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401