Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EN73_RS03755 Genome accession   NZ_CP007632
Coordinates   690742..691527 (+) Length   261 a.a.
NCBI ID   WP_000825430.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NGBS572     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 685742..696527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN73_RS10870 (EN73_03855) - 686859..687299 (+) 441 Protein_673 hypothetical protein -
  EN73_RS10875 (EN73_03860) - 687387..687653 (+) 267 WP_001865676.1 hypothetical protein -
  EN73_RS10880 (EN73_03865) - 687754..687882 (+) 129 WP_000962057.1 hypothetical protein -
  EN73_RS10885 (EN73_03870) - 687891..688211 (+) 321 WP_001865677.1 hypothetical protein -
  EN73_RS03745 (EN73_03875) - 688308..688979 (+) 672 WP_000891267.1 ATP-binding cassette domain-containing protein -
  EN73_RS03750 (EN73_03880) - 689036..690481 (-) 1446 WP_000750933.1 FAD/NAD(P)-binding protein -
  EN73_RS03755 (EN73_03885) endA 690742..691527 (+) 786 WP_000825430.1 DNA/RNA non-specific endonuclease Machinery gene
  EN73_RS03760 (EN73_03890) - 691605..692243 (-) 639 WP_000478529.1 VTT domain-containing protein -
  EN73_RS03765 (EN73_03895) - 692460..693116 (+) 657 WP_000121094.1 ATP-binding cassette domain-containing protein -
  EN73_RS03770 (EN73_03900) - 693113..693886 (+) 774 WP_000011926.1 ABC transporter permease -
  EN73_RS03775 (EN73_03905) - 694050..694868 (+) 819 WP_000601007.1 hypothetical protein -
  EN73_RS03780 (EN73_03910) - 694905..695789 (-) 885 WP_000354840.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 29396.85 Da        Isoelectric Point: 8.9927

>NTDB_id=106683 EN73_RS03755 WP_000825430.1 690742..691527(+) (endA) [Streptococcus agalactiae strain NGBS572]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDKTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=106683 EN73_RS03755 WP_000825430.1 690742..691527(+) (endA) [Streptococcus agalactiae strain NGBS572]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAAAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGGCATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

52.02

75.862

0.395
  endA Streptococcus pneumoniae D39

52.02

75.862

0.395
  endA Streptococcus pneumoniae R6

52.02

75.862

0.395
  endA Streptococcus pneumoniae TIGR4

52.02

75.862

0.395

Multiple sequence alignment