Detailed information NTG0106530

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: EG64_RS07185
• Genome accession: NZ_CP007606
• Coordinates: 1475644..1478220 (+)
• Length: 858 a.a.
• NCBI ID: WP_038418222.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain BM013B
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1470644..1483220

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EG64_RS07150 (EG64_07485)	-	1472502..1473280 (-)	779	Protein_1367	DNA methyltransferase	-
EG64_RS07160 (EG64_07495)	-	1473470..1474258 (+)	789	WP_080279686.1	integrase	-
EG64_RS07165 (EG64_07500)	-	1474362..1474841 (+)	480	WP_000571125.1	hypothetical protein	-
EG64_RS07170 (EG64_07505)	comB2	1474838..1475122 (+)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
EG64_RS07175 (EG64_07510)	comB3	1475133..1475396 (+)	264	WP_001177716.1	hypothetical protein	Machinery gene
EG64_RS07180 (EG64_07515)	-	1475408..1475644 (+)	237	WP_038418221.1	hypothetical protein	-
EG64_RS07185 (EG64_07520)	comB4	1475644..1478220 (+)	2577	WP_038418222.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
EG64_RS08520 (EG64_07525)	-	1478217..1478357 (+)	141	WP_000789926.1	hypothetical protein	-
EG64_RS07195 (EG64_07530)	-	1478350..1479486 (+)	1137	WP_038418224.1	VirB8/TrbF family protein	-
EG64_RS07200 (EG64_07535)	-	1479483..1481138 (+)	1656	WP_038418226.1	TrbG/VirB9 family P-type conjugative transfer protein	-
EG64_RS07205 (EG64_07540)	comB10	1481135..1482334 (+)	1200	WP_038418227.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98668.68 Da
• Isoelectric Point: 8.7611

>NTDB_id=106530 EG64_RS07185 WP_038418222.1 1475644..1478220(+) (comB4) [Helicobacter pylori strain BM013B]
MLESALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENGNSSNETHSNTSSNKDKKNKFKKKITFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTDILDSSFEYYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMINKEINKIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2577 bp

>NTDB_id=106530 EG64_RS07185 WP_038418222.1 1475644..1478220(+) (comB4) [Helicobacter pylori strain BM013B]
ATGTTAGAAAGCGCCCTTAAATATTGCAAGGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGGAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAGACATTTTAGATAGCAGTTTTGAATACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCCTACTATGTCTTTCATAAGATGATTGACAGAGCCTTAAAAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATAAATAAAGAAATCAATAAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.087	98.019	0.462