Detailed information NTG0106446

Bioinformatically predicted

Overview

• Name: amiF
• Type: Regulator
• Locus tag: AABA19_RS08905
• Genome accession: NZ_AP028609
• Coordinates: 1756208..1757134 (-)
• Length: 308 a.a.
• NCBI ID: WP_001291296.1
• Uniprot ID: A0A0T8U5M2
• Organism: Streptococcus pneumoniae strain Sep4
• Function: internalize XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1754826..1756132	1756208..1757134	flank	76

Gene organization within MGE regions

Location: 1754826..1757134

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA19_RS08900	-	1754826..1756132 (+)	1307	Protein_1764	transposase	-
AABA19_RS08905 (TKY121806_17710)	amiF	1756208..1757134 (-)	927	WP_001291296.1	ATP-binding cassette domain-containing protein	Regulator

Sequence

Protein

• Length: 308 a.a.
• Molecular weight: 34769.82 Da
• Isoelectric Point: 6.6224

>NTDB_id=106446 AABA19_RS08905 WP_001291296.1 1756208..1757134(-) (amiF) [Streptococcus pneumoniae strain Sep4]
MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGESGSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSRE
QAAELIRRIQMIFQDPAASLNERATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFISDRIAVIYKGVIVEVAETEELFN
NPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHDYETDKPSMVEIRPGHYVWANQAELARYQKGLN

Nucleotide

• Length: 927 bp

>NTDB_id=106446 AABA19_RS08905 WP_001291296.1 1756208..1757134(-) (amiF) [Streptococcus pneumoniae strain Sep4]
ATGTCTGAAAAATTAGTAGAAATCAAAGATTTAGAAATTTCCTTCGGTGAAGGAAGTAAGAAGTTTGTCGCGGTTAAAAA
TGCTAACTTCTTTATCAACAAGGGAGAAACTTTCTCGCTTGTAGGTGAGTCCGGTAGTGGGAAAACAACTATTGGTCGTG
CTATCATCGGTCTAAATGATACAAGTAATGGAGATATCATTTTTGATGGTCAAAAGATTAATGGTAAGAAATCGCGTGAA
CAAGCTGCGGAATTGATTCGTCGAATCCAGATGATTTTCCAAGACCCTGCCGCAAGTTTGAATGAACGTGCGACTGTTGA
TTATATTATTTCTGAAGGTCTTTACAATCACCGTTTATTTAAGGATGAAGAAGAACGTAAAGAGAAAGTTCAAAGTATTA
TCCGTGAAGTAGGTCTTCTTGCTGAGCACTTGACTCGTTACCCTCATGAATTCTCAGGCGGTCAACGTCAACGTATCGGT
ATTGCCCGTGCCTTGGTCATGCAACCAGACTTTGTTATTGCAGATGAGCCAATTTCAGCCTTGGACGTTTCTGTACGTGC
CCAAGTCTTGAACTTGCTCAAAAAATTCCAAAAAGAGCTCGGCTTGACCTATCTCTTCATCGCCCATGACTTGTCGGTTG
TTCGCTTTATTTCAGATCGTATCGCAGTTATTTACAAGGGTGTTATTGTAGAGGTTGCAGAAACAGAAGAATTGTTTAAC
AATCCAATTCACCCATATACTCAAGCCTTGCTTTCAGCGGTACCAATCCCAGATCCAATCTTGGAACGTAAGAAGGTCTT
GAAGGTTTACGACCCAAGTCAACACGACTATGAGACTGATAAGCCATCTATGGTAGAAATCCGTCCAGGTCACTATGTTT
GGGCGAACCAAGCCGAATTAGCACGTTATCAAAAAGGACTAAACTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (25-178)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (230-262)

3D structure

• AlphaFold DB: A0A0T8U5M2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiF	Streptococcus thermophilus LMG 18311	85.574	99.026	0.847
amiF	Streptococcus salivarius strain HSISS4	85.574	99.026	0.847
amiF	Streptococcus thermophilus LMD-9	85.246	99.026	0.844