Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AAA996_RS09290 Genome accession   NZ_AP028606
Coordinates   1817259..1818083 (-) Length   274 a.a.
NCBI ID   WP_001036783.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep1     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1812259..1823083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA996_RS09285 (TKY121773_18200) - 1815637..1816968 (-) 1332 WP_000390042.1 hemolysin family protein -
  AAA996_RS09290 (TKY121773_18210) endA 1817259..1818083 (-) 825 WP_001036783.1 DNA-entry nuclease EndA Machinery gene
  AAA996_RS09295 (TKY121773_18220) - 1818122..1818310 (-) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  AAA996_RS09300 (TKY121773_18230) murA 1818303..1819586 (-) 1284 WP_000358027.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AAA996_RS09305 (TKY121773_18240) - 1819610..1819840 (-) 231 WP_000615437.1 DUF1146 family protein -
  AAA996_RS09310 (TKY121773_18250) sepM 1819898..1820935 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  AAA996_RS09315 (TKY121773_18260) coaD 1820919..1821407 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  AAA996_RS09320 (TKY121773_18270) rsmD 1821397..1821936 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AAA996_RS09325 (TKY121773_18280) asnA 1822001..1822993 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.66 Da        Isoelectric Point: 10.1700

>NTDB_id=106224 AAA996_RS09290 WP_001036783.1 1817259..1818083(-) (endA) [Streptococcus pneumoniae strain Sep1]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=106224 AAA996_RS09290 WP_001036783.1 1817259..1818083(-) (endA) [Streptococcus pneumoniae strain Sep1]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993

Multiple sequence alignment