Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | ACFKHK_RS09955 | Genome accession | NZ_CP170760 |
| Coordinates | 1894092..1895045 (-) | Length | 317 a.a. |
| NCBI ID | WP_392462068.1 | Uniprot ID | - |
| Organism | Streptococcus parasuis strain FZ2 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1852027..1927113 | 1894092..1895045 | within | 0 |
Gene organization within MGE regions
Location: 1852027..1927113
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACFKHK_RS09730 | tcrZ | 1852584..1852790 (-) | 207 | WP_002335389.1 | copper chaperone TcrZ | - |
| ACFKHK_RS09735 | - | 1852815..1853015 (-) | 201 | Protein_1889 | HAD family hydrolase | - |
| ACFKHK_RS09740 | gap | 1853310..1854311 (-) | 1002 | WP_171989921.1 | type I glyceraldehyde-3-phosphate dehydrogenase | - |
| ACFKHK_RS09745 | - | 1854609..1855199 (-) | 591 | WP_174846436.1 | YdhK family protein | - |
| ACFKHK_RS09750 | - | 1855512..1855967 (-) | 456 | WP_039671262.1 | CopY/TcrY family copper transport repressor | - |
| ACFKHK_RS09755 | - | 1856535..1856900 (-) | 366 | WP_253952800.1 | hypothetical protein | - |
| ACFKHK_RS09760 | - | 1856900..1857364 (-) | 465 | WP_171989923.1 | replication initiator protein A | - |
| ACFKHK_RS09765 | - | 1857366..1857556 (-) | 191 | Protein_1895 | hypothetical protein | - |
| ACFKHK_RS09770 | - | 1857749..1858921 (+) | 1173 | WP_392462037.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| ACFKHK_RS09775 | - | 1859015..1859713 (+) | 699 | WP_171989926.1 | ATP-binding cassette domain-containing protein | - |
| ACFKHK_RS09780 | - | 1859723..1861348 (+) | 1626 | WP_392462040.1 | hypothetical protein | - |
| ACFKHK_RS09785 | ald | 1861450..1862547 (+) | 1098 | WP_392462042.1 | alanine dehydrogenase | - |
| ACFKHK_RS09790 | - | 1862669..1863691 (-) | 1023 | WP_216806357.1 | YeiH family protein | - |
| ACFKHK_RS09795 | - | 1863701..1864024 (-) | 324 | WP_174846424.1 | AzlD domain-containing protein | - |
| ACFKHK_RS09800 | - | 1864011..1864712 (-) | 702 | WP_171989929.1 | AzlC family ABC transporter permease | - |
| ACFKHK_RS09805 | - | 1865043..1865831 (-) | 789 | WP_277745447.1 | ABC transporter permease subunit | - |
| ACFKHK_RS09810 | - | 1865828..1866661 (-) | 834 | WP_274504954.1 | ABC transporter ATP-binding protein | - |
| ACFKHK_RS09815 | tsaD | 1866651..1867688 (-) | 1038 | WP_392462045.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD | - |
| ACFKHK_RS09820 | rimI | 1867678..1868118 (-) | 441 | WP_130554967.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| ACFKHK_RS09825 | tsaB | 1868115..1868798 (-) | 684 | WP_392462047.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB | - |
| ACFKHK_RS09830 | - | 1869034..1869213 (-) | 180 | WP_277940764.1 | hypothetical protein | - |
| ACFKHK_RS09835 | - | 1869536..1869766 (+) | 231 | WP_024392378.1 | RNA polymerase epsilon subunit | - |
| ACFKHK_RS09840 | rnjA | 1869770..1871449 (+) | 1680 | WP_239604291.1 | ribonuclease J1 | - |
| ACFKHK_RS09845 | glnA | 1871781..1873127 (-) | 1347 | WP_171989726.1 | type I glutamate--ammonia ligase | - |
| ACFKHK_RS09850 | - | 1873155..1873526 (-) | 372 | WP_024392055.1 | MerR family transcriptional regulator | - |
| ACFKHK_RS09855 | - | 1873602..1874117 (-) | 516 | WP_024392054.1 | aromatic acid exporter family protein | - |
| ACFKHK_RS09860 | - | 1874766..1875965 (-) | 1200 | WP_392462051.1 | phosphoglycerate kinase | - |
| ACFKHK_RS09865 | - | 1876103..1876945 (-) | 843 | WP_392462053.1 | aldo/keto reductase | - |
| ACFKHK_RS09870 | - | 1876963..1878159 (-) | 1197 | WP_216806349.1 | iron-containing alcohol dehydrogenase | - |
| ACFKHK_RS09875 | gap | 1878347..1879357 (-) | 1011 | WP_174846416.1 | type I glyceraldehyde-3-phosphate dehydrogenase | - |
| ACFKHK_RS09880 | fusA | 1879584..1881665 (-) | 2082 | WP_171989721.1 | elongation factor G | - |
| ACFKHK_RS09885 | rpsG | 1881996..1882466 (-) | 471 | WP_105182784.1 | 30S ribosomal protein S7 | - |
| ACFKHK_RS09890 | rpsL | 1882483..1882896 (-) | 414 | WP_105130854.1 | 30S ribosomal protein S12 | - |
| ACFKHK_RS09895 | groL | 1883126..1884748 (-) | 1623 | WP_392462056.1 | chaperonin GroEL | - |
| ACFKHK_RS09900 | groES | 1884847..1885128 (-) | 282 | WP_171989719.1 | co-chaperone GroES | - |
| ACFKHK_RS09905 | ssbA | 1885698..1886093 (-) | 396 | WP_392462058.1 | single-stranded DNA-binding protein | Machinery gene |
| ACFKHK_RS09910 | - | 1886175..1887107 (+) | 933 | WP_392462059.1 | alpha/beta fold hydrolase | - |
| ACFKHK_RS09915 | ytpR | 1887176..1887799 (-) | 624 | WP_392462060.1 | YtpR family tRNA-binding protein | - |
| ACFKHK_RS09920 | - | 1887818..1888774 (-) | 957 | WP_392462062.1 | DUF1002 domain-containing protein | - |
| ACFKHK_RS09925 | - | 1888818..1889138 (-) | 321 | WP_392462064.1 | thioredoxin family protein | - |
| ACFKHK_RS09930 | - | 1889135..1889419 (-) | 285 | WP_392462066.1 | DUF4651 domain-containing protein | - |
| ACFKHK_RS09935 | pepA | 1889632..1890693 (+) | 1062 | WP_277940770.1 | glutamyl aminopeptidase | - |
| ACFKHK_RS09940 | - | 1890738..1891994 (-) | 1257 | WP_392462675.1 | bifunctional folylpolyglutamate synthase/dihydrofolate synthase | - |
| ACFKHK_RS09945 | - | 1892049..1892600 (-) | 552 | WP_216806342.1 | folate family ECF transporter S component | - |
| ACFKHK_RS09950 | - | 1892855..1894042 (-) | 1188 | WP_239604301.1 | acetate kinase | - |
| ACFKHK_RS09955 | comYH | 1894092..1895045 (-) | 954 | WP_392462068.1 | class I SAM-dependent methyltransferase | Machinery gene |
| ACFKHK_RS09960 | comGG | 1895065..1895565 (-) | 501 | WP_171989710.1 | competence type IV pilus minor pilin ComGG | - |
| ACFKHK_RS09965 | comYF | 1895543..1895977 (-) | 435 | WP_174846408.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| ACFKHK_RS09970 | comGE | 1895964..1896257 (-) | 294 | WP_171989708.1 | competence type IV pilus minor pilin ComGE | - |
| ACFKHK_RS09975 | comGD | 1896229..1896633 (-) | 405 | WP_171989707.1 | competence type IV pilus minor pilin ComGD | - |
| ACFKHK_RS09980 | comYC | 1896617..1896901 (-) | 285 | WP_171989706.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| ACFKHK_RS09985 | comYB | 1896903..1897940 (-) | 1038 | WP_171989705.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| ACFKHK_RS09990 | comYA | 1897852..1898802 (-) | 951 | WP_392462071.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| ACFKHK_RS09995 | - | 1898890..1899840 (+) | 951 | WP_277940773.1 | S66 peptidase family protein | - |
| ACFKHK_RS10000 | - | 1899873..1900241 (-) | 369 | WP_277943115.1 | DUF1033 family protein | - |
| ACFKHK_RS10005 | rpoC | 1900366..1904010 (-) | 3645 | WP_171989701.1 | DNA-directed RNA polymerase subunit beta' | - |
| ACFKHK_RS10010 | rpoB | 1904188..1907760 (-) | 3573 | WP_174846402.1 | DNA-directed RNA polymerase subunit beta | - |
| ACFKHK_RS10015 | pbp1b | 1908420..1910825 (-) | 2406 | WP_239604306.1 | penicillin-binding protein PBP1B | - |
| ACFKHK_RS10020 | tyrS | 1910972..1912231 (+) | 1260 | WP_392462074.1 | tyrosine--tRNA ligase | - |
| ACFKHK_RS10025 | - | 1912529..1912966 (-) | 438 | WP_392462076.1 | DUF1492 domain-containing protein | - |
| ACFKHK_RS10030 | - | 1913370..1913933 (-) | 564 | Protein_1948 | hypothetical protein | - |
| ACFKHK_RS10035 | - | 1914114..1914287 (-) | 174 | WP_392462078.1 | hypothetical protein | - |
| ACFKHK_RS10040 | - | 1914624..1916126 (-) | 1503 | WP_392462080.1 | phage/plasmid primase, P4 family | - |
| ACFKHK_RS10045 | - | 1916146..1917015 (-) | 870 | WP_392462082.1 | primase alpha helix C-terminal domain-containing protein | - |
| ACFKHK_RS10050 | - | 1917150..1917431 (-) | 282 | WP_392462084.1 | XRE family transcriptional regulator | - |
| ACFKHK_RS10055 | - | 1917424..1917759 (-) | 336 | WP_392462085.1 | hypothetical protein | - |
| ACFKHK_RS10060 | - | 1917756..1917905 (-) | 150 | WP_392462087.1 | hypothetical protein | - |
| ACFKHK_RS10065 | - | 1917892..1918107 (-) | 216 | WP_392462089.1 | hypothetical protein | - |
| ACFKHK_RS10070 | - | 1918333..1918536 (-) | 204 | WP_277945849.1 | hypothetical protein | - |
| ACFKHK_RS10075 | - | 1918533..1918766 (-) | 234 | WP_392462091.1 | hypothetical protein | - |
| ACFKHK_RS10080 | - | 1919219..1919848 (-) | 630 | WP_392462093.1 | Rha family transcriptional regulator | - |
| ACFKHK_RS10085 | - | 1919866..1920066 (-) | 201 | WP_029188910.1 | helix-turn-helix transcriptional regulator | - |
| ACFKHK_RS10090 | - | 1920275..1920769 (+) | 495 | WP_392462095.1 | helix-turn-helix domain-containing protein | - |
| ACFKHK_RS10095 | - | 1921504..1922649 (+) | 1146 | WP_392462097.1 | tyrosine-type recombinase/integrase | - |
| ACFKHK_RS10100 | - | 1922822..1923199 (+) | 378 | WP_239604307.1 | HIT family protein | - |
| ACFKHK_RS10105 | - | 1923311..1924021 (+) | 711 | WP_239604308.1 | PASTA domain-containing protein | - |
| ACFKHK_RS10110 | - | 1924070..1924279 (-) | 210 | WP_130554922.1 | heavy-metal-associated domain-containing protein | - |
| ACFKHK_RS10115 | - | 1924447..1924896 (-) | 450 | WP_392462100.1 | CopY/TcrY family copper transport repressor | - |
| ACFKHK_RS10120 | - | 1924997..1926505 (-) | 1509 | WP_392462676.1 | zinc ABC transporter substrate-binding protein AdcA | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35592.78 Da Isoelectric Point: 4.5696
>NTDB_id=1059286 ACFKHK_RS09955 WP_392462068.1 1894092..1895045(-) (comYH) [Streptococcus parasuis strain FZ2]
MKYEKIEQAYNLLLENVQTIQNQLGTNIYDAMIEQNAAYVAGQHEPELVLNNNQVLRELALTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVSTPRVTVLEIGSGTGNLAQTVLNASQKELDYLGIEIDDLLIDLSASIADVMGAA
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARPLTPFVYPLQSLQEPEAIQKFMVNFKNWKQENAI
MKYEKIEQAYNLLLENVQTIQNQLGTNIYDAMIEQNAAYVAGQHEPELVLNNNQVLRELALTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVSTPRVTVLEIGSGTGNLAQTVLNASQKELDYLGIEIDDLLIDLSASIADVMGAA
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARPLTPFVYPLQSLQEPEAIQKFMVNFKNWKQENAI
Nucleotide
Download Length: 954 bp
>NTDB_id=1059286 ACFKHK_RS09955 WP_392462068.1 1894092..1895045(-) (comYH) [Streptococcus parasuis strain FZ2]
ATGAAATATGAAAAAATTGAACAGGCCTACAACCTGCTTTTAGAAAATGTACAGACAATTCAAAATCAACTTGGGACCAA
TATTTATGATGCTATGATTGAGCAAAATGCTGCCTATGTAGCTGGTCAACATGAACCCGAACTTGTTCTCAACAACAATC
AAGTCTTGAGAGAATTAGCCTTGACAAAGGAAGAATGGCGTCGTGCTTACCAATTCTTGCTCATTAAAGCTAACCAGACA
GAACCGATGCAGTACAACCATCAGTTCACACCTGACTCTATCGGATTTATCTTATCTTTCCTTGTGGACCAGTTGGTCTC
TACTCCAAGAGTGACGGTTTTGGAAATTGGTTCTGGTACAGGAAACTTAGCTCAGACCGTTCTCAACGCCAGCCAGAAGG
AATTAGACTATTTAGGGATTGAAATAGATGACCTCTTGATTGATTTATCGGCTAGTATCGCGGATGTCATGGGAGCAGCT
ATTTCATTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAAGAAAGCCAAGTGATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGTTATCAGGTAGCTAGTCCAAATGAACATACCTACGCCCATCATTTGCTCA
TGGAACAGTCCCTCAAATATCTGGAAAAAGATGGATTTGCGATTTTACTGGCTCCAAATGATTTATTAACGAGTCCGCAA
AGCGATTTATTAAAAGGTTGGTTACAAGAACAAGCCAATATTGTTGCCATGATTGCCCTGCCGCCAAATCTTTTTGGGAA
GGCTGCCATGGCCAAGTCCATTTTTGTGTTACAAAAGAAAGCTGCCAGACCTTTAACTCCTTTCGTTTATCCTTTGCAAA
GCCTGCAAGAACCAGAAGCGATTCAGAAGTTCATGGTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTGA
ATGAAATATGAAAAAATTGAACAGGCCTACAACCTGCTTTTAGAAAATGTACAGACAATTCAAAATCAACTTGGGACCAA
TATTTATGATGCTATGATTGAGCAAAATGCTGCCTATGTAGCTGGTCAACATGAACCCGAACTTGTTCTCAACAACAATC
AAGTCTTGAGAGAATTAGCCTTGACAAAGGAAGAATGGCGTCGTGCTTACCAATTCTTGCTCATTAAAGCTAACCAGACA
GAACCGATGCAGTACAACCATCAGTTCACACCTGACTCTATCGGATTTATCTTATCTTTCCTTGTGGACCAGTTGGTCTC
TACTCCAAGAGTGACGGTTTTGGAAATTGGTTCTGGTACAGGAAACTTAGCTCAGACCGTTCTCAACGCCAGCCAGAAGG
AATTAGACTATTTAGGGATTGAAATAGATGACCTCTTGATTGATTTATCGGCTAGTATCGCGGATGTCATGGGAGCAGCT
ATTTCATTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAAGAAAGCCAAGTGATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGTTATCAGGTAGCTAGTCCAAATGAACATACCTACGCCCATCATTTGCTCA
TGGAACAGTCCCTCAAATATCTGGAAAAAGATGGATTTGCGATTTTACTGGCTCCAAATGATTTATTAACGAGTCCGCAA
AGCGATTTATTAAAAGGTTGGTTACAAGAACAAGCCAATATTGTTGCCATGATTGCCCTGCCGCCAAATCTTTTTGGGAA
GGCTGCCATGGCCAAGTCCATTTTTGTGTTACAAAAGAAAGCTGCCAGACCTTTAACTCCTTTCGTTTATCCTTTGCAAA
GCCTGCAAGAACCAGAAGCGATTCAGAAGTTCATGGTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA140 |
59.177 |
99.685 |
0.59 |
| comYH | Streptococcus mutans UA159 |
58.861 |
99.685 |
0.587 |