Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DI45_RS07940 Genome accession   NZ_CP007560
Coordinates   1534951..1535733 (-) Length   260 a.a.
NCBI ID   WP_047235454.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS743     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1529951..1540733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DI45_RS07915 (DI45_08220) gatB 1530048..1531487 (-) 1440 WP_009880806.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  DI45_RS07920 (DI45_08225) gatA 1531487..1532953 (-) 1467 WP_011528911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DI45_RS07925 (DI45_08230) gatC 1532953..1533255 (-) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DI45_RS07930 (DI45_08235) - 1533487..1533711 (-) 225 WP_002988560.1 putative PEP-binding protein -
  DI45_RS07935 (DI45_08240) - 1534250..1534804 (-) 555 WP_002983281.1 cysteine hydrolase family protein -
  DI45_RS07940 (DI45_08245) codY 1534951..1535733 (-) 783 WP_047235454.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DI45_RS07945 (DI45_08250) - 1535951..1537165 (-) 1215 WP_047235455.1 pyridoxal phosphate-dependent aminotransferase -
  DI45_RS07950 (DI45_08255) - 1537396..1537848 (+) 453 WP_002992571.1 universal stress protein -
  DI45_RS07955 (DI45_08260) - 1537971..1539359 (-) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  DI45_RS07960 (DI45_08265) - 1539431..1540396 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28651.80 Da        Isoelectric Point: 4.5611

>NTDB_id=105557 DI45_RS07940 WP_047235454.1 1534951..1535733(-) (codY) [Streptococcus pyogenes strain NGAS743]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTMLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=105557 DI45_RS07940 WP_047235454.1 1534951..1535733(-) (codY) [Streptococcus pyogenes strain NGAS743]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACAATGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.759

98.846

0.65
  codY Bacillus subtilis subsp. subtilis str. 168

50.98

98.077

0.5

Multiple sequence alignment