Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ACB691_RS18860 Genome accession   NZ_CP169739
Coordinates   3704034..3704813 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus paranthracis strain mr-1B     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3677413..3723445 3704034..3704813 within 0


Gene organization within MGE regions


Location: 3677413..3723445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB691_RS18740 - 3677607..3677858 (-) 252 WP_001239753.1 YlmC/YmxH family sporulation protein -
  ACB691_RS18745 - 3677985..3679226 (-) 1242 WP_000592994.1 pitrilysin family protein -
  ACB691_RS18750 - 3679313..3680212 (-) 900 WP_000857421.1 polysaccharide deacetylase family protein -
  ACB691_RS18755 pnp 3680365..3682503 (-) 2139 WP_000076746.1 polyribonucleotide nucleotidyltransferase -
  ACB691_RS18760 rpsO 3682664..3682933 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  ACB691_RS18765 ribF 3683034..3684005 (-) 972 WP_000766710.1 bifunctional riboflavin kinase/FAD synthetase -
  ACB691_RS18770 truB 3684049..3684972 (-) 924 WP_000399341.1 tRNA pseudouridine(55) synthase TruB -
  ACB691_RS18775 rbfA 3685059..3685415 (-) 357 WP_000776443.1 30S ribosome-binding factor RbfA -
  ACB691_RS18780 - 3685431..3685712 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  ACB691_RS18785 infB 3685709..3687769 (-) 2061 WP_000036342.1 translation initiation factor IF-2 -
  ACB691_RS18790 - 3687774..3688085 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  ACB691_RS18795 rnpM 3688086..3688358 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  ACB691_RS18800 nusA 3688370..3689476 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  ACB691_RS18805 rimP 3689494..3689964 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  ACB691_RS18810 - 3690297..3694598 (-) 4302 WP_000059980.1 PolC-type DNA polymerase III -
  ACB691_RS18815 - 3694723..3696423 (-) 1701 WP_000814314.1 proline--tRNA ligase -
  ACB691_RS18820 rseP 3696533..3697789 (-) 1257 WP_001090249.1 RIP metalloprotease RseP -
  ACB691_RS18825 dxr 3697806..3698948 (-) 1143 WP_000790362.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  ACB691_RS18830 cdsA 3698972..3699763 (-) 792 WP_000813584.1 phosphatidate cytidylyltransferase -
  ACB691_RS18835 uppS 3699781..3700557 (-) 777 WP_000971301.1 isoprenyl transferase -
  ACB691_RS18840 frr 3700643..3701200 (-) 558 WP_000531500.1 ribosome recycling factor -
  ACB691_RS18845 pyrH 3701203..3701925 (-) 723 WP_000042663.1 UMP kinase -
  ACB691_RS18850 tsf 3701992..3702879 (-) 888 WP_001018580.1 translation elongation factor Ts -
  ACB691_RS18855 rpsB 3702983..3703684 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  ACB691_RS18860 codY 3704034..3704813 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ACB691_RS18865 hslU 3704891..3706282 (-) 1392 WP_000550081.1 ATP-dependent protease ATPase subunit HslU -
  ACB691_RS18870 hslV 3706305..3706847 (-) 543 WP_000526271.1 ATP-dependent protease proteolytic subunit HslV -
  ACB691_RS18875 xerC 3706890..3707789 (-) 900 WP_001101228.1 tyrosine recombinase XerC -
  ACB691_RS18880 trmFO 3707855..3709159 (-) 1305 WP_001998091.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  ACB691_RS18885 topA 3709210..3711288 (-) 2079 WP_001286973.1 type I DNA topoisomerase -
  ACB691_RS18890 dprA 3711433..3712302 (-) 870 WP_000818025.1 DNA-processing protein DprA -
  ACB691_RS18895 sucD 3712390..3713292 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  ACB691_RS18900 sucC 3713312..3714472 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  ACB691_RS18905 rnhB 3714666..3715439 (-) 774 WP_001174725.1 ribonuclease HII -
  ACB691_RS18910 ylqF 3715491..3716381 (-) 891 WP_000236700.1 ribosome biogenesis GTPase YlqF -
  ACB691_RS18915 lepB 3716402..3716953 (-) 552 WP_000711857.1 signal peptidase I -
  ACB691_RS18920 rplS 3717055..3717399 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  ACB691_RS18925 trmD 3717546..3718280 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  ACB691_RS18930 rimM 3718280..3718795 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  ACB691_RS18935 - 3718916..3719143 (-) 228 WP_000737403.1 KH domain-containing protein -
  ACB691_RS18940 rpsP 3719158..3719430 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  ACB691_RS18945 ffh 3719531..3720880 (-) 1350 WP_000863461.1 signal recognition particle protein -
  ACB691_RS18950 - 3720893..3721225 (-) 333 WP_000891062.1 putative DNA-binding protein -
  ACB691_RS18955 ftsY 3721359..3722348 (-) 990 WP_000007646.1 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=1052714 ACB691_RS18860 WP_000421288.1 3704034..3704813(-) (codY) [Bacillus paranthracis strain mr-1B]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=1052714 ACB691_RS18860 WP_000421288.1 3704034..3704813(-) (codY) [Bacillus paranthracis strain mr-1B]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGCTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATTGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCAGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTACTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment