Detailed information NTG0104459

Bioinformatically predicted

Overview

• Name: proC
• Type: Machinery gene
• Locus tag: R8493_RS05385
• Genome accession: NZ_AP028341
• Coordinates: 1034507..1035244 (+)
• Length: 245 a.a.
• NCBI ID: WP_002824859.1
• Uniprot ID: A0A2A4L6Q8
• Organism: Campylobacter coli strain BCH-10328
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1029507..1040244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8493_RS05355 (B10328_10390)	rpsF	1029654..1030031 (+)	378	WP_002777082.1	30S ribosomal protein S6	-
R8493_RS05360 (B10328_10400)	-	1030040..1030588 (+)	549	WP_002777084.1	single-stranded DNA-binding protein	-
R8493_RS05365 (B10328_10410)	rpsR	1030599..1030859 (+)	261	WP_002777087.1	30S ribosomal protein S18	-
R8493_RS05370 (B10328_10420)	lon	1030916..1033291 (-)	2376	WP_215431912.1	endopeptidase La	-
R8493_RS05375 (B10328_10430)	-	1033307..1033954 (-)	648	WP_002780248.1	outer membrane protein assembly factor BamD	-
R8493_RS05380 (B10328_10440)	fliW	1034118..1034507 (+)	390	WP_002777093.1	flagellar assembly protein FliW	-
R8493_RS05385 (B10328_10450)	proC	1034507..1035244 (+)	738	WP_002824859.1	pyrroline-5-carboxylate reductase	Machinery gene
R8493_RS05390 (B10328_10460)	-	1035241..1035546 (+)	306	WP_052784994.1	hypothetical protein	-
R8493_RS05395 (B10328_10470)	-	1035539..1036207 (+)	669	WP_301754001.1	hypothetical protein	-
R8493_RS05400 (B10328_10480)	-	1036204..1036656 (+)	453	WP_002777117.1	hypothetical protein	-
R8493_RS05405 (B10328_10490)	-	1036649..1037278 (-)	630	WP_002824854.1	uroporphyrinogen-III synthase	-
R8493_RS05410 (B10328_10500)	thiE	1037256..1037888 (-)	633	WP_002824853.1	thiamine phosphate synthase	-
R8493_RS05415 (B10328_10510)	thiD	1037878..1038690 (-)	813	WP_317647044.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
R8493_RS05420 (B10328_10520)	-	1038690..1039373 (-)	684	WP_002824849.1	3-methyladenine DNA glycosylase	-
R8493_RS05425 (B10328_10530)	-	1039370..1040131 (-)	762	WP_072215388.1	ATP-binding protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 26811.23 Da
• Isoelectric Point: 9.4758

>NTDB_id=104459 R8493_RS05385 WP_002824859.1 1034507..1035244(+) (proC) [Campylobacter coli strain BCH-10328]
MKADLYILANGAMAQALAYGLKDSYNIYIVGRNLEKLQILEKEGFKTLLYKDFNIENKNIILAFKPYALESVAANLKGKA
KILISVLANTDFDKLRLIQAQNYARIMPNTAAKYKASTTPYVLKNSNFKDEIIEILNTFGKAYALNEEKQMNAAMAISGC
APAFLALVAESIANAGVYEGLSKELSLNLTRSLFKSAATLLENEHPAIIKENICSPAGVTIKGIKVLEQKGIRGTFFEAL
NASAT

Nucleotide

• Length: 738 bp

>NTDB_id=104459 R8493_RS05385 WP_002824859.1 1034507..1035244(+) (proC) [Campylobacter coli strain BCH-10328]
ATGAAAGCTGATTTATATATACTTGCTAATGGTGCGATGGCGCAAGCTTTGGCTTATGGATTAAAAGATTCTTATAATAT
CTATATAGTCGGTAGAAATTTAGAAAAACTTCAAATTTTAGAAAAAGAAGGTTTTAAAACTTTACTCTATAAAGATTTTA
ATATAGAAAATAAAAATATTATCTTAGCTTTTAAACCTTATGCCTTAGAAAGTGTCGCAGCAAATTTAAAAGGCAAGGCA
AAAATTTTAATTTCAGTTTTAGCCAATACGGATTTTGATAAATTAAGACTTATCCAAGCCCAAAATTATGCAAGGATAAT
GCCAAATACAGCAGCTAAATATAAAGCTTCCACAACTCCTTATGTTTTAAAAAATTCAAATTTTAAAGATGAAATCATAG
AAATTTTAAATACTTTTGGCAAAGCTTATGCGTTAAACGAAGAAAAACAAATGAATGCTGCCATGGCTATAAGCGGTTGC
GCTCCTGCTTTTTTAGCATTAGTAGCTGAAAGCATTGCCAATGCTGGTGTGTATGAAGGATTATCAAAAGAGCTGAGTTT
AAATCTCACTCGTTCGCTTTTTAAAAGTGCTGCAACCTTGCTAGAAAACGAGCACCCAGCCATCATTAAGGAAAATATTT
GCTCGCCTGCAGGTGTTACTATAAAAGGGATTAAAGTATTAGAGCAAAAAGGTATCCGTGGGACTTTCTTTGAGGCTCTT
AATGCTAGTGCAACATGA

Domains

Predicted by InterproScan.

• NADP oxidoreductase coenzyme F420-dependent (F420_oxidored) (7-88)

• Pyrroline-5-carboxylate reductase dimerisation (P5CR_dimer) (148-244)

3D structure

• AlphaFold DB: A0A2A4L6Q8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
proC	Campylobacter jejuni subsp. jejuni 81-176	80.833	97.959	0.792