Detailed information NTG1044053

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACEPX0_RS09930
• Genome accession: NZ_CP168436
• Coordinates: 2026101..2027144 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain P3L22A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021101..2032144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEPX0_RS09900 (ACEPX0_09900)	-	2021522..2022778 (-)	1257	WP_001793983.1	aminopeptidase	-
ACEPX0_RS09905 (ACEPX0_09905)	-	2022781..2022981 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACEPX0_RS09910 (ACEPX0_09910)	-	2023128..2023592 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
ACEPX0_RS09915 (ACEPX0_09915)	-	2023599..2023874 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACEPX0_RS09920 (ACEPX0_09920)	-	2024152..2025369 (+)	1218	Protein_1916	YihY/virulence factor BrkB family protein	-
ACEPX0_RS09925 (ACEPX0_09925)	vraR	2025482..2026111 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACEPX0_RS09930 (ACEPX0_09930)	vraS	2026101..2027144 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACEPX0_RS09935 (ACEPX0_09935)	liaF	2027141..2027842 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACEPX0_RS09940 (ACEPX0_09940)	-	2027857..2028243 (-)	387	WP_001110178.1	hypothetical protein	-
ACEPX0_RS09945 (ACEPX0_09945)	map	2028460..2029218 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACEPX0_RS09950 (ACEPX0_09950)	-	2029918..2030904 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
ACEPX0_RS09955 (ACEPX0_09955)	-	2031093..2031506 (-)	414	WP_001643743.1	hypothetical protein	-
ACEPX0_RS09960 (ACEPX0_09960)	-	2031535..2031644 (-)	110	Protein_1924	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1044053 ACEPX0_RS09930 WP_001017131.1 2026101..2027144(-) (vraS) [Staphylococcus aureus strain P3L22A]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1044053 ACEPX0_RS09930 WP_001017131.1 2026101..2027144(-) (vraS) [Staphylococcus aureus strain P3L22A]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1