Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   DXE64_RS03180 Genome accession   NZ_LT992470
Coordinates   634322..636670 (-) Length   782 a.a.
NCBI ID   WP_001249297.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 13_LA_301     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 629322..641670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE64_RS03160 - 630792..631406 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  DXE64_RS03165 uvrC 631730..633511 (-) 1782 WP_000390534.1 excinuclease ABC subunit UvrC Machinery gene
  DXE64_RS03170 - 633677..633772 (+) 96 WP_016187496.1 hypothetical protein -
  DXE64_RS03175 trxA 633835..634149 (-) 315 WP_001018928.1 thioredoxin -
  DXE64_RS03180 mutS/mutS2 634322..636670 (-) 2349 WP_001249297.1 endonuclease MutS2 Machinery gene
  DXE64_RS03185 polX 636680..638392 (-) 1713 WP_000161944.1 DNA polymerase/3'-5' exonuclease PolX -
  DXE64_RS03190 - 638465..638986 (-) 522 WP_000582581.1 CvpA family protein -
  DXE64_RS03195 zapA 638994..639253 (-) 260 Protein_597 cell division protein ZapA -
  DXE64_RS03200 rnhC 639628..640566 (+) 939 WP_001284271.1 ribonuclease HIII -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 88722.36 Da        Isoelectric Point: 6.1692

>NTDB_id=1034010 DXE64_RS03180 WP_001249297.1 634322..636670(-) (mutS/mutS2) [Staphylococcus aureus isolate 13_LA_301]
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADI
GGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRS
KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISR
LRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVA
NTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNI
VEILKRADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTY
KLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQ
QFQNYEKSLIEDAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIV
AGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIE
LDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRVGMPSEGGFGVTVATLK

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=1034010 DXE64_RS03180 WP_001249297.1 634322..636670(-) (mutS/mutS2) [Staphylococcus aureus isolate 13_LA_301]
ATGAGACAAAAAACATTAGACGTCTTAGAATTTGAAAAAATAAAATCACTCGTTGCCAATGAAACTATAAGTGACTTAGG
CTTGGAAAAGGTCAATCAAATGATGCCAGCTACTAATTTTGAAACGGTTGTTTTTCAAATGGAAGAAACGGATGAGATTG
CTCAAATCTATAATAAGCATCGTTTACCAAGCTTGAGTGGCTTATCTAAAGTATCAGCATTCATTCATCGCGCTGATATT
GGCGGCGTTTTAAATGTATCAGAGCTTAACTTGATAAAAAGATTAATTCAAGTACAAAATCAATTTAAGACATTTTATAA
TCAATTGGTTGAAGAAGATGAAGGTGTTAAATACCCAATATTAGATGACAAGATGAATCAATTACCTGTGTTAACCGATC
TTTTTCAACAAATAAATGAAACATGCGATACGTATGATTTATATGATAATGCGAGTTATGAATTGCAAGGGATTAGAAGT
AAAATTTCTAGCACGAATCAACGTATTAGACAAAATTTGGACCGTATTGTTAAAAGCCAAGCAAATCAGAAAAAATTATC
AGATGCTATTGTAACAGTTAGGAATGAAAGAAACGTTATACCTGTCAAAGCTGAATATCGACAAGATTTTAATGGGATTG
TACATGATCAATCTGCTTCAGGACAAACATTGTATATTGAGCCATCATCAGTTGTTGAAATGAATAATCAAATTAGTCGA
TTACGTCATGATGAAGCAATTGAAAAAGAACGCATTTTAACGCAACTAACTGGTTATGTTGCTGCGGACAAAGATGCACT
ACTTGTGGCAGAACAAGTCATGGGTCAGTTAGATTTTTTAATCGCAAAAGCGAGATATAGTAGAAGTATTAAAGGAACAA
AGCCGATATTTAAAGAGGAACGTACTGTATATTTACCTAAAGCATACCATCCATTATTAAATCGTGAGACTGTTGTAGCT
AATACCATCGAATTTATGGAAGATATTGAAACGGTAATTATTACAGGACCGAATACAGGTGGTAAAACAGTAACATTAAA
AACATTAGGTTTAATTATTGTTATGGCTCAATCAGGATTATTGATTCCAACACTTGATGGTAGTCAGTTAAGTGTATTTA
AAAATGTATATTGCGATATCGGAGATGAACAATCAATAGAACAATCATTATCAACTTTTTCATCTCATATGACGAATATA
GTTGAAATTTTAAAGCGTGCAGACAAACATAGTTTAGTTTTATTTGATGAATTAGGTGCAGGTACAGATCCAAGTGAAGG
TGCTGCCTTAGCAATGAGCATTTTAGACCATGTTAGAAAAATTGGTTCTCTAGTAATGGCAACGACGCACTATCCTGAAC
TTAAAGCATATAGTTATAATCGAGAAGGCGTTATGAATGCGAGTGTAGAATTTGATGTAGATACATTAAGCCCAACTTAT
AAATTGTTAATGGGAGTACCAGGTCGTTCCAATGCTTTTGATATTTCTAAAAAGTTAGGTCTTAGTTTGAACATTATAAA
TAAGGCTAAGACGATGATTGGTACTGATGAAAAAGAAATAAATGAAATGATTGAGTCATTAGAGCGTAATTACAAACGTG
TAGAGACACAGAGGTTAGAACTGGACCGTCTTGTAAAAGAAGCGGAGCAAGTGCATGATGATTTATCTAAGCAGTATCAA
CAATTCCAAAATTATGAAAAATCTCTAATTGAAGATGCTAAAGAAAAAGCGAATCAAAAAATTAAAGCAGCAACAAAAGA
AGCTGACGATATTATTAAAGACCTAAGACAATTGCGTGAACAAAAAGGTGCAGATGTTAAAGAACATGAATTGATTGATA
AGAAGAAACGATTAGATGATCATTATGAAGCGAAATCTATAAAGCAAAATGTACAAAAGCAAAAATACGATAAAATTGTT
GCTGGTGATGAAGTAAAAGTATTATCTTACGGTCAAAAGGGTGAAGTTTTAGAAATTGTCAATGATGAAGAAGCAATTGT
TCAAATGGGAATTATTAAAATGAAGTTACCTATTGAAGATTTAGAGAAAAAACAAAAAGAAAAAGTTAAGCCAACGAAAA
TGGTTACACGTCAAAATCGTCAAACAATTAAAACTGAACTTGATTTACGAGGCTATCGTTATGAGGATGCTTTAATTGAA
CTAGATCAATATTTAGATCAAGCCGTTTTAAGTAATTACGAACAAGTTTATATCATTCATGGTAAAGGTACAGGTGCACT
TCAAAAAGGTGTACAACAACATTTGAAAAAGCATAAAAGTGTTAGTGACTTTAGAGTTGGTATGCCAAGTGAAGGTGGAT
TTGGCGTTACCGTTGCAACACTAAAATAA

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(641-681)

MutS domain V (MutS_V)

(332-512)

Smr domain (Smr)

(707-782)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

49.81

100

0.503