Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DXE63_RS11220 Genome accession   NZ_LT992458
Coordinates   2167823..2168596 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus isolate 7_4623     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2162823..2173596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE63_RS11185 - 2163076..2163846 (-) 771 WP_000473705.1 isoprenyl transferase -
  DXE63_RS11190 frr 2164219..2164773 (-) 555 WP_001280006.1 ribosome recycling factor -
  DXE63_RS11195 pyrH 2164792..2165514 (-) 723 WP_000057330.1 UMP kinase -
  DXE63_RS11200 tsf 2165651..2166532 (-) 882 WP_000201387.1 translation elongation factor Ts -
  DXE63_RS11205 - 2166567..2166680 (-) 114 WP_001789890.1 hypothetical protein -
  DXE63_RS11210 rpsB 2166714..2167481 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  DXE63_RS11215 - 2167680..2167772 (-) 93 WP_001790530.1 hypothetical protein -
  DXE63_RS11220 codY 2167823..2168596 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DXE63_RS11225 hslU 2168621..2170024 (-) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  DXE63_RS11230 hslV 2170090..2170635 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  DXE63_RS11235 xerC 2170632..2171528 (-) 897 WP_001015606.1 tyrosine recombinase XerC -
  DXE63_RS11240 trmFO 2171945..2173252 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=1033067 DXE63_RS11220 WP_000055337.1 2167823..2168596(-) (codY) [Staphylococcus aureus isolate 7_4623]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=1033067 DXE63_RS11220 WP_000055337.1 2167823..2168596(-) (codY) [Staphylococcus aureus isolate 7_4623]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTTATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAG

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment