Detailed information NTG1026475

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: STN4L_RS09235
• Genome accession: NZ_LS974444
• Coordinates: 1736284..1737069 (+)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain N4L
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1731284..1742069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STN4L_RS09210 (STN4L_02172)	pflA	1731560..1732360 (+)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-
STN4L_RS09215 (STN4L_02174)	-	1732572..1732946 (+)	375	WP_011681547.1	membrane protein	-
STN4L_RS10120 (STN4L_02175)	-	1733007..1733180 (+)	174	WP_167401590.1	hypothetical protein	-
STN4L_RS09220	-	1733252..1733823 (-)	572	Protein_1714	IS30 family transposase	-
STN4L_RS09225 (STN4L_02178)	-	1734003..1734455 (-)	453	WP_002946987.1	universal stress protein	-
STN4L_RS09230 (STN4L_02179)	-	1734810..1736024 (+)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
STN4L_RS09235 (STN4L_02180)	codY	1736284..1737069 (+)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
STN4L_RS09240 (STN4L_02181)	-	1737132..1737683 (+)	552	WP_002946999.1	cysteine hydrolase family protein	-
STN4L_RS09245 (STN4L_02182)	-	1737807..1738655 (+)	849	WP_014608646.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
STN4L_RS09250 (STN4L_02183)	msrA	1738667..1739176 (+)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
STN4L_RS09255	-	1739329..1740773 (+)	1445	Protein_1721	6-phospho-beta-glucosidase	-
STN4L_RS09260 (STN4L_02187)	-	1741101..1741298 (+)	198	WP_014608644.1	glycosyltransferase	-
STN4L_RS09265 (STN4L_02188)	-	1741311..1741565 (+)	255	WP_024010053.1	glycosyl transferase	-
STN4L_RS09270 (STN4L_02189)	gatC	1741705..1742007 (+)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=1026475 STN4L_RS09235 WP_002951720.1 1736284..1737069(+) (codY) [Streptococcus thermophilus strain N4L]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=1026475 STN4L_RS09235 WP_002951720.1 1736284..1737069(+) (codY) [Streptococcus thermophilus strain N4L]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACATTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502