Detailed information NTG1025748

Bioinformatically predicted

Overview

• Name: recD2
• Type: Machinery gene
• Locus tag: AB3451_RS12970
• Genome accession: NZ_CP162445
• Coordinates: 2606343..2608820 (-)
• Length: 825 a.a.
• NCBI ID: WP_001283312.1
• Uniprot ID: A0A7U7EYY0
• Organism: Staphylococcus aureus strain TUM22178
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2601343..2613820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3451_RS12945 (AB3451_12945)	-	2601369..2602007 (-)	639	WP_000342266.1	O-methyltransferase	-
AB3451_RS12950 (AB3451_12950)	-	2602292..2602600 (-)	309	WP_117200976.1	DUF1292 domain-containing protein	-
AB3451_RS12955 (AB3451_12955)	ruvX	2602615..2603043 (-)	429	WP_000939059.1	Holliday junction resolvase RuvX	-
AB3451_RS12960 (AB3451_12960)	-	2603047..2603307 (-)	261	WP_000426912.1	IreB family regulatory phosphoprotein	-
AB3451_RS12965 (AB3451_12965)	alaS	2603370..2606000 (-)	2631	WP_000734072.1	alanine--tRNA ligase	-
AB3451_RS12970 (AB3451_12970)	recD2	2606343..2608820 (-)	2478	WP_001283312.1	ATP-dependent RecD-like DNA helicase	Machinery gene
AB3451_RS12975 (AB3451_12975)	-	2608822..2609490 (-)	669	WP_000567030.1	tetratricopeptide repeat protein	-
AB3451_RS12980 (AB3451_12980)	mnmA	2610071..2611189 (-)	1119	WP_000066094.1	tRNA 2-thiouridine(34) synthase MnmA	-
AB3451_RS12985 (AB3451_12985)	-	2611190..2612332 (-)	1143	WP_000409158.1	cysteine desulfurase family protein	-
AB3451_RS12990 (AB3451_12990)	-	2612644..2613657 (+)	1014	WP_000985895.1	LLM class flavin-dependent oxidoreductase	-

Sequence

Protein

• Length: 825 a.a.
• Molecular weight: 92958.74 Da
• Isoelectric Point: 4.4945

>NTDB_id=1025748 AB3451_RS12970 WP_001283312.1 2606343..2608820(-) (recD2) [Staphylococcus aureus strain TUM22178]
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAE
TFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
IRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQG
HTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIE
QSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLA
APTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQ
LPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAV
NKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFW
AKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLL
GDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVL
TEATMFKIDPMINMGEITPYDFIER

Nucleotide

• Length: 2478 bp

>NTDB_id=1025748 AB3451_RS12970 WP_001283312.1 2606343..2608820(-) (recD2) [Staphylococcus aureus strain TUM22178]
ATGTCAGACCCTACACTATTTGATTATTCAATGATCAAAGGTACTGTTGAAGCGATATTGTTTCAAAACAGTGATAATTT
TTATACAGTGCTTAAAGTAGATACTATTGAAACAAATGAAGACTTTGATACAATGCCAACTGTTGTAGGGTTTCTTCCGA
ATATTGTTGAAGGCGATGTCTACACATTTAAAGGGCAAGTTGTTGATCATCCACGTTATGGTAAACAATTAAAAGCAGAG
ACTTTTGAAAAAGAAATGCCACAAACGAAAGAAGCAATTATAAGTTATTTATCTAGTGATTTGTTTAAAGGTGTAGGTAA
AAAGACAGCTCAAAATATTGTTAATACATTAGGTGACAATGCGATAAATGATATATTAGATGACCATTCAGTGCTAGAAA
AAGTTTCGGGATTATCTAAAAAGAAACAGAAACAAATTGCAGAACAAATTTCAGCAAATCAAGAATCTGAAAAAATAATG
ATTCGTTTACATGATTTAGGGTTTGGTCCTAAACTTTCAATGGCAATTTATCAGTTTTATCTCGGCGATACACTGACTAT
TTTAGATCGAAATCCATATCAATTGATTTATGATATTAAAGGTATTGGTTTTAATAAAGCAGATCAACTTGCTAGAAATA
TTGGTATCGCTTATAACGATAATGAACGATTAAAAGCTGCGTTGCTCTATACGTTAGAAGAAGAATGTATTAAACAGGGA
CATACATATTTGCCTATCAATGTTGTTATAGATTTAACGGTTGATGTATTAAATTATCAAGATGAAGAGGTCATCGAACC
TGAAAAATTAGACGAAATGTTGCAATACTTAAATGAGGAAAAACGACTAATTATTGACAATGAACAAGTTGCAATTCCAA
GTTTGTATTATTCTGAAATCAAAAGTGTTCAAAACTTATTCAGAATAAAGACGCATACAAATAAACTTACAGAAATTGAA
CAGTCAGATTTACAAATGCATATTGGTGAAATAGAAGATGCGAATCAAGTGAACTATGCAGCTTCACAAAAAGAAGCTTT
GCAAACGGCTATCAATTCTAAGGTGATGCTATTAACCGGTGGACCGGGAACAGGAAAAACGACAGTAATTAAAGGTATTG
TTGAATTATATGCTGAGATTCATGGCTTATCATTAGATTATGATGATTATGTCAATGATGATTATCCAGTTGTATTAGCA
GCGCCAACAGGAAGAGCGTCCAAGAGACTACAAGAGTCAACTGGATTAGAAGCTATGACGATTCATCGTTTAATAGGTTG
GAATCAAGACACAAAGCCAGAGGATATATTAGAAAATGAAATAAACGCACGACTCATAATCATTGATGAGATGTCTATGG
TAGATACTTGGTTGTTCCACCAATTTTTAAGTGCAGTTCCTTTAGATGCACAATTGATATTTGTAGGTGATGAGGACCAA
TTGCCTTCTGTAGGTCCTGGTCAAGTATTTAAAGATTTAATTGAATCGAAAGCTATACCACGAGTTAATCTGACTGAAGT
ATATCGTCAACAAGATGGTTCAAGCATTATAGAATTAGCACATCGAATGAAGTTGGGTCAGAAAATTGATATTACACAGC
GTTTTCATGATAGAAGTTTTATTAACTGTCAGGCAAACCAAATACCAACAGTTGTAGAGAAGGTAGTTACTAGTGCTGTT
AATAAAGGGTATACTATGGCTGATATTCAAGTGCTTGCACCAATGTATAAAGGAAATGCCGGTATTAAACGTTTAAATCA
AGTTTTACAAGATATTTTAAACCCTAAAAAGAAAGACACACGAGAAATTGAGTTTGGTGATGTAGTCTTTAGAAAAGGTG
ACAAAGTATTACAACTTGTTAATAGGCCAAATGATAACATATTCAATGGTGACATAGGAGTTATTGTTGGTATTTTTTGG
GCGAAAGAAAATGCCCTTAATAAAGATGTACTTGTTGTGGATTTTGAAGGTAATGAAATTACATTTACGAAACAAGATAT
GATGGAATTAACACATGCTTATTGTACATCAATCCATAAATCACAAGGTTCAGAATTTCCTATTGTTATCATGCCTATTG
TTAAACAGTATTTTAGAATGTTACAAAGACCGATATTATATACTGGTTTAACTAGAGCGAAAACGAGTTTAGTTCTACTT
GGTGATCCAGAAGCATTTGATATTGGATTAAAAACAAATGGTCAAGCGCGTTTAACACAATTATGTACATTGTTGAAAAA
TTATTTTAATTCAGAAGATGAAGAAATGCTGGAAAACACAGCAACTAATGATACAGGAGCTTCACAAACGACAATAGATG
ATCAAGTAGAAGCGCCAATGTCATCGAATGATAGTGGAGAAGTTACGTCTGATTCAACAAAAACAGATATAAATGTATTA
ACGGAAGCTACAATGTTTAAAATTGACCCAATGATTAATATGGGAGAAATCACGCCGTATGACTTTATAGAACGTTGA

Domains

Predicted by InterproScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (585-655)

• AAA domain (AAA_30) (339-544)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (672-720)

• Helix-hairpin-helix containing domain (HHH_RecD2) (153-243)

3D structure

• AlphaFold DB: A0A7U7EYY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD2	Bacillus subtilis subsp. subtilis str. 168	52.988	91.273	0.484