Detailed information NTG1025597

Bioinformatically predicted

Overview

• Name: recD2
• Type: Machinery gene
• Locus tag: AB3446_RS04450
• Genome accession: NZ_CP162440
• Coordinates: 893202..895679 (-)
• Length: 825 a.a.
• NCBI ID: WP_001283312.1
• Uniprot ID: A0A7U7EYY0
• Organism: Staphylococcus aureus strain TUM22457
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 888202..900679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3446_RS04425 (AB3446_04425)	-	888228..888866 (-)	639	WP_000342258.1	O-methyltransferase	-
AB3446_RS04430 (AB3446_04430)	-	889151..889459 (-)	309	WP_000134779.1	DUF1292 domain-containing protein	-
AB3446_RS04435 (AB3446_04435)	ruvX	889474..889902 (-)	429	WP_000939059.1	Holliday junction resolvase RuvX	-
AB3446_RS04440 (AB3446_04440)	-	889906..890166 (-)	261	WP_000426912.1	IreB family regulatory phosphoprotein	-
AB3446_RS04445 (AB3446_04445)	alaS	890229..892859 (-)	2631	WP_000734075.1	alanine--tRNA ligase	-
AB3446_RS04450 (AB3446_04450)	recD2	893202..895679 (-)	2478	WP_001283312.1	ATP-dependent RecD-like DNA helicase	Machinery gene
AB3446_RS04455 (AB3446_04455)	-	895681..896349 (-)	669	WP_000567017.1	tetratricopeptide repeat protein	-
AB3446_RS04460 (AB3446_04460)	mnmA	897044..898162 (-)	1119	WP_000066097.1	tRNA 2-thiouridine(34) synthase MnmA	-
AB3446_RS04465 (AB3446_04465)	-	898163..899305 (-)	1143	WP_000409157.1	cysteine desulfurase family protein	-
AB3446_RS04470 (AB3446_04470)	-	899617..900630 (+)	1014	WP_000985878.1	LLM class flavin-dependent oxidoreductase	-

Sequence

Protein

• Length: 825 a.a.
• Molecular weight: 92958.74 Da
• Isoelectric Point: 4.4945

>NTDB_id=1025597 AB3446_RS04450 WP_001283312.1 893202..895679(-) (recD2) [Staphylococcus aureus strain TUM22457]
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAE
TFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
IRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQG
HTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIE
QSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLA
APTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQ
LPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAV
NKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFW
AKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLL
GDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVL
TEATMFKIDPMINMGEITPYDFIER

Nucleotide

• Length: 2478 bp

>NTDB_id=1025597 AB3446_RS04450 WP_001283312.1 893202..895679(-) (recD2) [Staphylococcus aureus strain TUM22457]
ATGTCAGACCCTACACTATTTGATTATTCAATGATCAAAGGTACTGTTGAAGCGATATTGTTTCAAAACAGTGATAATTT
TTATACAGTGCTTAAAGTAGATACTATTGAAACAAATGAAGACTTTGATACAATGCCAACTGTTGTAGGGTTTCTTCCGA
ATATTGTTGAAGGCGATGTCTACACATTTAAAGGGCAAGTTGTTGATCATCCACGTTATGGTAAACAATTAAAAGCAGAG
ACTTTTGAAAAAGAAATGCCACAAACGAAAGAAGCAATTATAAGTTATTTATCTAGTGATTTGTTTAAAGGTGTAGGTAA
AAAGACAGCTCAAAATATTGTTAATACATTAGGTGACAATGCGATAAATGATATATTAGATGACCATTCAGTGCTAGAAA
AAGTTTCGGGATTATCTAAAAAGAAACAGAAACAAATTGCAGAACAAATTTCAGCAAATCAAGAATCTGAAAAAATAATG
ATTCGTTTACATGATTTAGGGTTTGGTCCTAAACTTTCAATGGCAATTTATCAGTTTTATCTCGGCGATACACTGACTAT
TTTAGATCGAAATCCATATCAATTGATTTATGATATTAAAGGTATTGGTTTTAATAAAGCAGATCAACTTGCTAGAAATA
TTGGTATCGCTTATAACGATAATGAACGATTAAAAGCTGCGTTGCTCTATACGTTAGAAGAAGAATGTATTAAACAGGGA
CATACATATTTGCCTATCAATGTTGTTATAGATTTAACGGTTGATGTATTAAATTATCAAGATGAAGAGGTCATCGAACC
TGAAAAATTAGACGAAATGTTGCAATACTTAAATGAGGAAAAACGACTAATTATTGACAATGAACAAGTTGCAATTCCAA
GTTTGTATTATTCTGAAATCAAAAGTGTTCAAAACTTATTCAGAATAAAGACGCATACAAATAAACTTACGGAAATTGAA
CAGTCAGATTTACAAATGCATATTGGTGAAATAGAAGATGCGAATCAAGTGAACTATGCAGCTTCACAAAAAGAAGCTTT
GCAAACGGCTATCAATTCTAAGGTGATGCTATTAACCGGTGGACCGGGAACAGGAAAGACGACAGTAATTAAAGGTATTG
TAGAATTATATGCTGAGATTCATGGCTTATCATTAGATTATGATGATTATGTCAATGATGATTATCCAGTTGTATTAGCA
GCGCCAACAGGAAGAGCGTCTAAGAGACTACAAGAGTCAACTGGATTAGAAGCAATGACGATTCATCGTTTAATAGGTTG
GAATCAAGACACAAAGCCAGAGGATATATTAGAAAATGAAATAAACGCACGACTCATAATCATTGATGAGATGTCTATGG
TAGATACTTGGTTGTTTCACCAATTTTTAAGTGCAGTTCCTTTAGATGCACAATTGATATTTGTAGGTGATGAGGACCAA
TTGCCTTCTGTAGGTCCTGGTCAAGTATTTAAAGATTTAATTGAATCGAAAGCTATACCACGAGTTAATCTGACTGAAGT
ATATCGTCAACAAGATGGTTCAAGCATTATAGAATTAGCACATCGAATGAAATTGGGTCAGAAAATTGATATTACACAGC
GTTTTCATGATAGAAGTTTTATTAACTGTCAGGCAAACCAAATACCAACAGTTGTTGAGAAGGTAGTTACTAGTGCTGTT
AATAAAGGGTATACTATGGCTGATATTCAAGTGCTTGCACCAATGTATAAAGGAAATGCCGGTATTAAACGTTTAAATCA
AGTTTTACAAGATATTTTAAACCCTAAAAAGAAAGACACACGAGAAATTGAGTTTGGTGATGTAGTCTTTAGAAAAGGTG
ACAAAGTATTACAACTTGTTAATAGGCCAAATGATAACATATTCAATGGTGACATAGGAGTTATTGTTGGTATTTTTTGG
GCGAAAGAAAATGCCCTTAATAAAGATGTACTTGTTGTGGATTTTGAAGGTAATGAAATTACATTTACGAAACAAGATAT
GATGGAATTAACACATGCTTATTGTACATCAATCCATAAATCACAAGGTTCAGAATTTCCTATTGTTATCATGCCTATTG
TTAAACAGTATTTTAGAATGTTACAAAGACCGATATTATATACTGGTTTAACTAGAGCGAAAACGAGTTTAGTTCTACTT
GGTGATCCAGAAGCATTTGATATTGGATTAAAAACAAATGGTCAAGCGCGTTTAACACAATTATGTACATTGTTGAAAAA
TTATTTTAATTCAGAAGATGAAGAAATGCTGGAAAACACAGCAACTAATGATACAGGAGCTTCACAAACGACAATAGATG
ATCAAGTAGAAGCGCCAATGTCATCGAATGATAGTGGAGAAGTTACGTCTGATTCAACAAAAACAGATATAAATGTATTA
ACGGAAGCTACAATGTTTAAAATTGACCCAATGATTAATATGGGAGAAATCACGCCGTATGACTTTATAGAACGTTGA

Domains

Predicted by InterproScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (585-655)

• AAA domain (AAA_30) (339-544)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (672-720)

• Helix-hairpin-helix containing domain (HHH_RecD2) (153-243)

3D structure

• AlphaFold DB: A0A7U7EYY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD2	Bacillus subtilis subsp. subtilis str. 168	52.988	91.273	0.484