Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   AB3454_RS12605 Genome accession   NZ_CP162418
Coordinates   2535825..2536895 (-) Length   356 a.a.
NCBI ID   WP_000776422.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM22750     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2530825..2541895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3454_RS12565 (AB3454_12565) gcvPA 2531002..2532348 (-) 1347 WP_117200971.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  AB3454_RS12570 (AB3454_12570) gcvT 2532368..2533459 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  AB3454_RS12575 (AB3454_12575) - 2533618..2534142 (-) 525 WP_001015121.1 shikimate kinase -
  AB3454_RS12580 (AB3454_12580) - 2534132..2534278 (-) 147 WP_001789879.1 hypothetical protein -
  AB3454_RS12585 (AB3454_12585) comGF 2534375..2534872 (-) 498 WP_001789864.1 competence type IV pilus minor pilin ComGF Machinery gene
  AB3454_RS12590 (AB3454_12590) comGE 2534790..2535089 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  AB3454_RS12595 (AB3454_12595) comGD 2535076..2535522 (-) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  AB3454_RS12600 (AB3454_12600) comGC 2535500..2535811 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  AB3454_RS12605 (AB3454_12605) comGB 2535825..2536895 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  AB3454_RS12610 (AB3454_12610) comGA 2536867..2537841 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  AB3454_RS12615 (AB3454_12615) - 2537893..2538516 (-) 624 WP_001223010.1 MBL fold metallo-hydrolase -
  AB3454_RS12620 (AB3454_12620) - 2538513..2538842 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  AB3454_RS12625 (AB3454_12625) - 2538842..2539828 (-) 987 WP_000161314.1 ROK family glucokinase -
  AB3454_RS12630 (AB3454_12630) - 2539825..2540028 (-) 204 WP_000087561.1 YqgQ family protein -
  AB3454_RS12635 (AB3454_12635) - 2540009..2541472 (-) 1464 WP_001017865.1 rhomboid family intramembrane serine protease -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41447.84 Da        Isoelectric Point: 10.0606

>NTDB_id=1025129 AB3454_RS12605 WP_000776422.1 2535825..2536895(-) (comGB) [Staphylococcus aureus strain TUM22750]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=1025129 AB3454_RS12605 WP_000776422.1 2535825..2536895(-) (comGB) [Staphylococcus aureus strain TUM22750]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCACAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

100

100

1
  comGB Staphylococcus aureus N315

100

100

1

Multiple sequence alignment