Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   DQN29_RS09470 Genome accession   NZ_LS483437
Coordinates   1823084..1823680 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain NCTC13751     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1818084..1828680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN29_RS09435 (NCTC13751_01883) - 1818141..1818446 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  DQN29_RS09440 (NCTC13751_01884) ruvX 1818458..1818877 (-) 420 WP_063632439.1 Holliday junction resolvase RuvX -
  DQN29_RS09445 (NCTC13751_01885) - 1818874..1819143 (-) 270 WP_063632440.1 IreB family regulatory phosphoprotein -
  DQN29_RS09450 (NCTC13751_01886) spx 1819257..1819655 (-) 399 WP_076639527.1 transcriptional regulator Spx -
  DQN29_RS09455 (NCTC13751_01887) recA 1819949..1821085 (-) 1137 WP_076639528.1 recombinase RecA Machinery gene
  DQN29_RS09460 (NCTC13751_01888) cinA 1821174..1822445 (-) 1272 WP_076639529.1 competence/damage-inducible protein A Machinery gene
  DQN29_RS09465 (NCTC13751_01889) - 1822514..1823074 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  DQN29_RS09470 (NCTC13751_01890) ruvA 1823084..1823680 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  DQN29_RS09475 (NCTC13751_01891) - 1823682..1824902 (-) 1221 WP_076639530.1 MDR family MFS transporter -
  DQN29_RS09480 (NCTC13751_01892) hexB 1824913..1826895 (-) 1983 WP_002992189.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=1024862 DQN29_RS09470 WP_002992186.1 1823084..1823680(-) (ruvA) [Streptococcus pyogenes strain NCTC13751]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=1024862 DQN29_RS09470 WP_002992186.1 1823084..1823680(-) (ruvA) [Streptococcus pyogenes strain NCTC13751]
ATGTACGACTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment