Detailed information NTG1024862

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ABW635_RS05850
• Genome accession: NZ_CP162310
• Coordinates: 1201456..1202319 (-)
• Length: 287 a.a.
• NCBI ID: WP_003099993.1
• Uniprot ID: A0A3L8GIC3
• Organism: Streptococcus iniae strain ZQ2205
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1196456..1207319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABW635_RS05830 (ABW635_05830)	-	1196710..1197090 (-)	381	WP_003099988.1	OsmC family protein	-
ABW635_RS05835 (ABW635_05835)	pheT	1197163..1199568 (-)	2406	WP_003099989.1	phenylalanine--tRNA ligase subunit beta	-
ABW635_RS05840 (ABW635_05840)	-	1199584..1200108 (-)	525	WP_003099991.1	N-acetyltransferase	-
ABW635_RS05845 (ABW635_05845)	pheS	1200121..1201164 (-)	1044	WP_003099992.1	phenylalanine--tRNA ligase subunit alpha	-
ABW635_RS05850 (ABW635_05850)	endA	1201456..1202319 (-)	864	WP_003099993.1	DNA/RNA non-specific endonuclease	Machinery gene
ABW635_RS05855 (ABW635_05855)	-	1202350..1202538 (-)	189	WP_003099995.1	DNA-directed RNA polymerase subunit beta	-
ABW635_RS05860 (ABW635_05860)	murA	1202542..1203813 (-)	1272	WP_003099997.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ABW635_RS05865 (ABW635_05865)	-	1203879..1204115 (-)	237	WP_071794729.1	DUF1146 family protein	-
ABW635_RS05870 (ABW635_05870)	-	1204191..1204607 (-)	417	WP_003100001.1	F0F1 ATP synthase subunit epsilon	-
ABW635_RS05875 (ABW635_05875)	atpD	1204620..1206026 (-)	1407	WP_003100002.1	F0F1 ATP synthase subunit beta	-
ABW635_RS05880 (ABW635_05880)	-	1206142..1207017 (-)	876	WP_003100004.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 31715.35 Da
• Isoelectric Point: 9.3865

>NTDB_id=1024862 ABW635_RS05850 WP_003099993.1 1201456..1202319(-) (endA) [Streptococcus iniae strain ZQ2205]
MSPKTKQSQKINLLLFLLVLVGLFYLIDSKEGEENNPIRAFYQSVMGASNQTSQKESSNPDTPSYALASSVLTEKVKRQL
GSKVEWNGNGAFVINDNSTNLDAKVSSAPYAHNQTRLLSGKKLPTVANALLAKSTRQYRDRNETGNGYSYWKPAGWHQIH
GLSGKYDHAVDRGHLLGYALVGGLKGFDASTSNSDNIATQLSWANQAMDSDSTGQNYYETKIRRALDKNKRVRYRVTLIY
EADNILASGSHLEAKSDDGSLEFNVFVPNVQKGLEVDYQTGQITVSH

Nucleotide

• Length: 864 bp

>NTDB_id=1024862 ABW635_RS05850 WP_003099993.1 1201456..1202319(-) (endA) [Streptococcus iniae strain ZQ2205]
ATGTCACCAAAGACAAAACAAAGTCAAAAAATCAATCTATTATTGTTTCTGCTTGTGCTCGTTGGCTTATTCTATTTGAT
TGATAGTAAAGAAGGGGAAGAGAATAATCCTATTCGAGCCTTTTATCAATCAGTGATGGGAGCTTCCAATCAAACTAGCC
AAAAAGAATCAAGCAATCCTGATACACCAAGTTATGCCTTGGCATCTTCGGTTTTAACAGAAAAAGTAAAAAGACAACTT
GGTTCGAAAGTTGAGTGGAATGGTAATGGTGCATTTGTCATCAATGATAACAGTACCAATTTGGATGCAAAAGTATCCAG
TGCTCCCTATGCTCACAATCAAACCAGACTCTTATCAGGGAAAAAGCTTCCAACAGTCGCCAATGCTTTACTTGCCAAAT
CAACAAGGCAATACCGAGACCGAAACGAGACCGGAAATGGCTACTCTTATTGGAAACCTGCTGGTTGGCACCAGATTCAT
GGTTTATCAGGAAAATATGATCACGCTGTGGACCGTGGGCATTTATTAGGCTATGCTTTAGTGGGAGGTCTTAAAGGATT
TGATGCCTCTACAAGCAATAGCGATAACATAGCAACGCAATTATCCTGGGCTAACCAAGCGATGGATAGTGATTCCACTG
GCCAAAATTATTATGAAACAAAAATCAGACGTGCATTGGACAAGAATAAGCGTGTCCGTTACCGTGTTACCCTCATTTAC
GAGGCTGATAATATATTAGCAAGTGGAAGCCATTTAGAAGCAAAATCAGATGACGGCAGTTTAGAATTTAACGTTTTTGT
GCCAAATGTTCAAAAAGGTCTAGAAGTTGACTATCAAACAGGACAAATAACAGTCAGTCACTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (95-245)

3D structure

• AlphaFold DB: A0A3L8GIC3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	63.559	82.23	0.523
endA	Streptococcus pneumoniae D39	63.559	82.23	0.523
endA	Streptococcus pneumoniae R6	63.559	82.23	0.523
endA	Streptococcus pneumoniae TIGR4	63.559	82.23	0.523