Detailed information NTG1024671

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: AB1F57_RS00235
• Genome accession: NZ_CP162268
• Coordinates: 32628..33362 (+)
• Length: 244 a.a.
• NCBI ID: WP_167785854.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZY1909104
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 27628..38362

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F57_RS00210 (AB1F57_00210)	pcsB	27739..28983 (+)	1245	WP_367985879.1	peptidoglycan hydrolase PcsB	-
AB1F57_RS00215 (AB1F57_00215)	-	29081..30046 (+)	966	WP_105111631.1	ribose-phosphate diphosphokinase	-
AB1F57_RS00220 (AB1F57_00220)	-	30140..31318 (+)	1179	WP_105111632.1	pyridoxal phosphate-dependent aminotransferase	-
AB1F57_RS00225 (AB1F57_00225)	recO	31305..32069 (+)	765	WP_367985880.1	DNA repair protein RecO	-
AB1F57_RS00230 (AB1F57_00230)	-	32261..32470 (+)	210	WP_367985881.1	hypothetical protein	-
AB1F57_RS00235 (AB1F57_00235)	comE/blpR	32628..33362 (+)	735	WP_167785854.1	response regulator transcription factor	Regulator
AB1F57_RS00240 (AB1F57_00240)	-	33359..34723 (+)	1365	WP_167785853.1	GHKL domain-containing protein	-
AB1F57_RS00245 (AB1F57_00245)	-	35046..35780 (+)	735	WP_167785852.1	hypothetical protein	-
AB1F57_RS00250 (AB1F57_00250)	-	35808..36683 (+)	876	WP_105128650.1	ABC transporter ATP-binding protein	-
AB1F57_RS00255 (AB1F57_00255)	-	36685..37455 (+)	771	WP_367985883.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 27995.87 Da
• Isoelectric Point: 5.2193

>NTDB_id=1024671 AB1F57_RS00235 WP_167785854.1 32628..33362(+) (comE/blpR) [Streptococcus sp. ZY1909104]
MLRIFILEDDFIQQARLEQAIEEAVKTSDVAYKTLEVFGKPQQLLEAVTETGNHQLFFLDIEIRGEEKKGMEIAREIRAR
DPHAVIVFVTTHSEFMPLTYKYRVSALDFIDKGLDEPAFKEAVADVLQHAYSHISQTVSDDAFVFKSEFSQIQVSFSDIL
YFETSSTPHKVVLTTKSGHTEFYGKVSDIAKTDERLYQSHRAYVVNPANILRVDAVERMVYFEQEESCLVSRMKLKGLLE
RVGK

Nucleotide

• Length: 735 bp

>NTDB_id=1024671 AB1F57_RS00235 WP_167785854.1 32628..33362(+) (comE/blpR) [Streptococcus sp. ZY1909104]
ATGTTACGGATTTTTATCTTGGAAGATGATTTTATACAACAAGCTAGGTTGGAGCAGGCGATTGAGGAAGCTGTAAAAAC
GAGTGACGTTGCCTATAAGACCTTAGAAGTGTTTGGTAAACCTCAGCAGTTATTAGAGGCTGTGACAGAGACTGGAAATC
ATCAGCTCTTTTTCCTAGATATTGAGATTAGAGGTGAGGAGAAGAAAGGGATGGAGATAGCACGGGAGATAAGGGCGCGT
GATCCGCATGCTGTGATTGTTTTTGTGACGACGCATTCGGAATTTATGCCTTTGACCTATAAATACCGTGTGTCAGCTCT
TGATTTTATTGATAAGGGGTTGGATGAGCCTGCCTTTAAAGAAGCGGTGGCAGATGTTCTCCAACATGCTTATAGTCATA
TTAGTCAGACTGTGAGCGATGATGCTTTTGTTTTCAAGAGTGAGTTTTCTCAGATTCAGGTGTCGTTTTCAGATATTTTG
TATTTTGAAACTTCTTCAACGCCTCATAAGGTCGTCTTGACAACCAAGTCAGGTCATACGGAGTTTTATGGCAAGGTGTC
AGATATTGCAAAAACGGATGAACGTTTGTACCAGAGCCATCGGGCTTATGTGGTCAATCCAGCTAATATTCTTCGTGTGG
ATGCTGTGGAGCGGATGGTTTATTTTGAACAGGAGGAATCTTGCTTGGTCTCTCGAATGAAACTGAAAGGTTTGCTAGAG
AGGGTTGGGAAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.812	97.951	0.537
comE/comE1	Streptococcus equinus JB1	45.607	97.951	0.447
comE/comE2	Streptococcus equinus JB1	39.916	97.541	0.389
comE	Streptococcus infantis strain Atu-4	36.508	100	0.377
comE/comE2	Streptococcus gordonii strain NCTC7865	37.449	99.59	0.373
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.449	99.59	0.373
comE	Streptococcus pneumoniae TIGR4	37.037	99.59	0.369
comE	Streptococcus mitis NCTC 12261	37.037	99.59	0.369
comE	Streptococcus mitis SK321	37.037	99.59	0.369
comE	Streptococcus pneumoniae Rx1	37.037	99.59	0.369
comE	Streptococcus pneumoniae D39	37.037	99.59	0.369
comE	Streptococcus pneumoniae R6	37.037	99.59	0.369