Detailed information NTG1023009

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: DQM79_RS07525
• Genome accession: NZ_LS483401
• Coordinates: 1471171..1473510 (-)
• Length: 779 a.a.
• NCBI ID: WP_002988252.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10085
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1466171..1478510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM79_RS07485 (NCTC10085_01480)	rpsR	1466562..1466801 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
DQM79_RS07490 (NCTC10085_01481)	ssb	1466966..1467457 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
DQM79_RS07495 (NCTC10085_01482)	rpsF	1467479..1467769 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
DQM79_RS07500 (NCTC10085_01483)	-	1467942..1468235 (-)	294	WP_002983113.1	hypothetical protein	-
DQM79_RS07505 (NCTC10085_01484)	mutY	1468403..1469557 (+)	1155	WP_002988276.1	A/G-specific adenine glycosylase	-
DQM79_RS07510 (NCTC10085_01485)	-	1469633..1470220 (+)	588	WP_002988273.1	helix-turn-helix domain-containing protein	-
DQM79_RS07515 (NCTC10085_01486)	trxA	1470272..1470604 (-)	333	WP_001932060.1	thioredoxin	-
DQM79_RS07520 (NCTC10085_01487)	-	1470667..1471167 (-)	501	WP_002988255.1	phosphatase PAP2 family protein	-
DQM79_RS07525 (NCTC10085_01488)	mutS/mutS2	1471171..1473510 (-)	2340	WP_002988252.1	endonuclease MutS2	Machinery gene
DQM79_RS07530 (NCTC10085_01489)	-	1473659..1474204 (-)	546	WP_002983087.1	CvpA family protein	-
DQM79_RS07535 (NCTC10085_01490)	-	1474207..1474515 (-)	309	WP_002988248.1	hypothetical protein	-
DQM79_RS07540 (NCTC10085_01491)	rnhC	1474672..1475574 (+)	903	WP_002988245.1	ribonuclease HIII	-
DQM79_RS07545 (NCTC10085_01492)	lepB	1475585..1476178 (+)	594	WP_002983074.1	signal peptidase I	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87871.08 Da
• Isoelectric Point: 6.4510

>NTDB_id=1023009 DQM79_RS07525 WP_002988252.1 1471171..1473510(-) (mutS/mutS2) [Streptococcus pyogenes strain NCTC10085]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKITVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFTLVRVQEEQKVKSKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=1023009 DQM79_RS07525 WP_002988252.1 1471171..1473510(-) (mutS/mutS2) [Streptococcus pyogenes strain NCTC10085]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
CCAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACACATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATCTCTGATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCCGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTACAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTGGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCCGAAACGCTTAGCCCCACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGATCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAGCGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGTCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATTAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGCTATGGACAGCGAGGTACTTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTACCCTTGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAGTAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATCCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCACGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGCGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• Smr domain (Smr) (704-778)

• MutS domain V (MutS_V) (324-505)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-669)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.506	100	0.411