Detailed information
Bioinformatically predicted
Overview
| Name | comGH | Type | Machinery gene |
| Locus tag | DQM97_RS00960 | Genome accession | NZ_LS483378 |
| Coordinates | 158320..159273 (+) | Length | 317 a.a. |
| NCBI ID | WP_019771347.1 | Uniprot ID | A0ABN5LFZ1 |
| Organism | Streptococcus sobrinus strain NCTC12279 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 153320..164273
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQM97_RS00910 (NCTC12279_00187) | comGA/cglA | 153741..154688 (+) | 948 | WP_002959503.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| DQM97_RS00915 (NCTC12279_00188) | comGB | 154612..155655 (+) | 1044 | WP_002959504.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| DQM97_RS00920 (NCTC12279_00189) | comGC | 155652..155978 (+) | 327 | WP_019770073.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| DQM97_RS00925 (NCTC12279_00190) | comGD | 155932..156366 (+) | 435 | WP_254051091.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| DQM97_RS00930 (NCTC12279_00191) | comGE | 156338..156631 (+) | 294 | WP_002959510.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| DQM97_RS00935 (NCTC12279_00192) | comGF | 156615..157052 (+) | 438 | WP_002959513.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| DQM97_RS00940 (NCTC12279_00193) | comGG | 157030..157491 (+) | 462 | WP_002959515.1 | competence type IV pilus minor pilin ComGG | Machinery gene |
| DQM97_RS00950 (NCTC12279_00195) | - | 157693..157959 (+) | 267 | WP_002959516.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| DQM97_RS00955 (NCTC12279_00196) | - | 157946..158221 (+) | 276 | WP_002959518.1 | helix-turn-helix domain-containing protein | - |
| DQM97_RS00960 (NCTC12279_00197) | comGH | 158320..159273 (+) | 954 | WP_019771347.1 | class I SAM-dependent methyltransferase | Machinery gene |
| DQM97_RS00965 (NCTC12279_00198) | - | 159336..160532 (+) | 1197 | WP_002959522.1 | acetate kinase | - |
| DQM97_RS00970 (NCTC12279_00199) | - | 161010..161915 (+) | 906 | WP_002959524.1 | LysR family transcriptional regulator | - |
| DQM97_RS00975 (NCTC12279_00200) | - | 162022..162288 (+) | 267 | WP_002959526.1 | ACT domain-containing protein | - |
| DQM97_RS00980 (NCTC12279_00201) | - | 162300..163637 (+) | 1338 | WP_002959528.1 | PFL family protein | - |
| DQM97_RS00985 | - | 163876..164178 (-) | 303 | Protein_154 | hypothetical protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35492.26 Da Isoelectric Point: 4.1537
>NTDB_id=1021368 DQM97_RS00960 WP_019771347.1 158320..159273(+) (comGH) [Streptococcus sobrinus strain NCTC12279]
MNFETIEKAYELLLENVQLLQNDLKTNSYDALIEQNAIYLDGKTENKTVLANDQALCDLNLSKEEWRRAYQFLFIKLAQS
EPLQANHQFTPDSIGFVLLFLLENLTKEASLDLLEIGSGTGNLAQTLLNNSSKGLNYLGLEVDDLLIDLSASIADVVGSD
ASFVQEDAVRPSLLKESDIIVSDLPVGYYPDDAIASRYQVAAQDDHTYAHHLLMEQSLKYLKANGFAIFLAPVNLLTSPQ
SDLLKAWLKGYADIVAVITLPEELFGNPANAKSIFVLQKQTVQAPETFVYPLSDLQDRDKLLDFMENFKKWSAEYIL
MNFETIEKAYELLLENVQLLQNDLKTNSYDALIEQNAIYLDGKTENKTVLANDQALCDLNLSKEEWRRAYQFLFIKLAQS
EPLQANHQFTPDSIGFVLLFLLENLTKEASLDLLEIGSGTGNLAQTLLNNSSKGLNYLGLEVDDLLIDLSASIADVVGSD
ASFVQEDAVRPSLLKESDIIVSDLPVGYYPDDAIASRYQVAAQDDHTYAHHLLMEQSLKYLKANGFAIFLAPVNLLTSPQ
SDLLKAWLKGYADIVAVITLPEELFGNPANAKSIFVLQKQTVQAPETFVYPLSDLQDRDKLLDFMENFKKWSAEYIL
Nucleotide
Download Length: 954 bp
>NTDB_id=1021368 DQM97_RS00960 WP_019771347.1 158320..159273(+) (comGH) [Streptococcus sobrinus strain NCTC12279]
ATGAATTTTGAAACGATTGAAAAAGCTTATGAGCTGCTATTAGAGAATGTTCAGCTCTTGCAAAATGACTTGAAGACCAA
TAGTTACGATGCCTTGATTGAGCAAAATGCTATCTATCTGGATGGCAAAACTGAAAATAAGACGGTTTTGGCCAATGACC
AGGCCTTGTGTGACTTGAATTTGAGCAAGGAAGAGTGGCGGAGGGCCTACCAGTTTCTCTTTATTAAGCTGGCCCAGTCT
GAACCCTTGCAGGCCAACCACCAGTTTACGCCGGATAGTATTGGTTTTGTCCTGCTTTTCTTGCTGGAAAATCTGACCAA
GGAAGCAAGTCTGGACCTTCTGGAGATTGGCTCTGGAACAGGCAATCTAGCTCAAACCCTGCTCAATAACAGCAGTAAAG
GTCTGAATTATCTGGGGCTAGAAGTGGATGATTTGCTGATTGATTTGTCAGCCAGCATCGCTGATGTTGTGGGATCTGAC
GCTAGTTTCGTGCAGGAGGATGCGGTTCGTCCTTCCCTGCTCAAGGAGAGCGACATTATTGTCAGCGATCTTCCCGTTGG
CTATTATCCCGATGATGCTATTGCCAGTCGCTACCAGGTGGCTGCCCAGGATGACCACACCTATGCCCATCACCTGCTTA
TGGAGCAGTCGCTCAAGTACTTGAAGGCCAATGGTTTTGCCATTTTCTTGGCTCCAGTCAATCTTCTGACCAGTCCCCAG
AGTGATCTGCTCAAGGCTTGGCTCAAGGGTTATGCTGACATCGTGGCCGTCATTACCCTACCTGAGGAACTTTTTGGCAA
TCCGGCCAATGCCAAGTCTATCTTTGTCCTGCAGAAGCAGACTGTTCAGGCGCCCGAGACCTTCGTCTATCCGCTGAGTG
ATTTGCAAGACCGAGATAAGCTCTTGGATTTTATGGAAAATTTCAAGAAATGGTCAGCTGAATATATTCTTTGA
ATGAATTTTGAAACGATTGAAAAAGCTTATGAGCTGCTATTAGAGAATGTTCAGCTCTTGCAAAATGACTTGAAGACCAA
TAGTTACGATGCCTTGATTGAGCAAAATGCTATCTATCTGGATGGCAAAACTGAAAATAAGACGGTTTTGGCCAATGACC
AGGCCTTGTGTGACTTGAATTTGAGCAAGGAAGAGTGGCGGAGGGCCTACCAGTTTCTCTTTATTAAGCTGGCCCAGTCT
GAACCCTTGCAGGCCAACCACCAGTTTACGCCGGATAGTATTGGTTTTGTCCTGCTTTTCTTGCTGGAAAATCTGACCAA
GGAAGCAAGTCTGGACCTTCTGGAGATTGGCTCTGGAACAGGCAATCTAGCTCAAACCCTGCTCAATAACAGCAGTAAAG
GTCTGAATTATCTGGGGCTAGAAGTGGATGATTTGCTGATTGATTTGTCAGCCAGCATCGCTGATGTTGTGGGATCTGAC
GCTAGTTTCGTGCAGGAGGATGCGGTTCGTCCTTCCCTGCTCAAGGAGAGCGACATTATTGTCAGCGATCTTCCCGTTGG
CTATTATCCCGATGATGCTATTGCCAGTCGCTACCAGGTGGCTGCCCAGGATGACCACACCTATGCCCATCACCTGCTTA
TGGAGCAGTCGCTCAAGTACTTGAAGGCCAATGGTTTTGCCATTTTCTTGGCTCCAGTCAATCTTCTGACCAGTCCCCAG
AGTGATCTGCTCAAGGCTTGGCTCAAGGGTTATGCTGACATCGTGGCCGTCATTACCCTACCTGAGGAACTTTTTGGCAA
TCCGGCCAATGCCAAGTCTATCTTTGTCCTGCAGAAGCAGACTGTTCAGGCGCCCGAGACCTTCGTCTATCCGCTGAGTG
ATTTGCAAGACCGAGATAAGCTCTTGGATTTTATGGAAAATTTCAAGAAATGGTCAGCTGAATATATTCTTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGH | Streptococcus mutans UA159 |
64.984 |
100 |
0.65 |
| comGH | Streptococcus mutans UA140 |
64.669 |
100 |
0.647 |