Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQM51_RS07960 Genome accession   NZ_LS483356
Coordinates   1497679..1498461 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain NCTC8230     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1492679..1503461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM51_RS07930 (NCTC8230_01578) gatB 1492777..1494216 (-) 1440 WP_111713344.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  DQM51_RS07935 (NCTC8230_01579) gatA 1494216..1495682 (-) 1467 WP_002983290.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQM51_RS07940 (NCTC8230_01580) gatC 1495682..1495984 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQM51_RS07945 - 1496216..1496440 (-) 225 WP_227874710.1 putative PEP-binding protein -
  DQM51_RS07955 (NCTC8230_01581) - 1496978..1497532 (-) 555 WP_002983281.1 cysteine hydrolase family protein -
  DQM51_RS07960 (NCTC8230_01582) codY 1497679..1498461 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQM51_RS07965 (NCTC8230_01583) - 1498678..1499892 (-) 1215 WP_011528914.1 pyridoxal phosphate-dependent aminotransferase -
  DQM51_RS07970 (NCTC8230_01584) - 1500123..1500575 (+) 453 WP_002983265.1 universal stress protein -
  DQM51_RS07975 (NCTC8230_01585) - 1500697..1502085 (-) 1389 WP_111713345.1 Cof-type HAD-IIB family hydrolase -
  DQM51_RS07980 (NCTC8230_01586) - 1502157..1503122 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=1019998 DQM51_RS07960 WP_002983278.1 1497679..1498461(-) (codY) [Streptococcus pyogenes strain NCTC8230]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1019998 DQM51_RS07960 WP_002983278.1 1497679..1498461(-) (codY) [Streptococcus pyogenes strain NCTC8230]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTAACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment