Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQL39_RS01000 Genome accession   NZ_LS483353
Coordinates   188723..189505 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain NCTC4001     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 183723..194505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL39_RS00980 (NCTC4001_00194) - 184060..185025 (-) 966 WP_111718047.1 asparaginase -
  DQL39_RS00985 (NCTC4001_00195) - 185097..186485 (+) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  DQL39_RS00990 (NCTC4001_00196) - 186608..187060 (-) 453 WP_002983265.1 universal stress protein -
  DQL39_RS00995 (NCTC4001_00197) - 187291..188505 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  DQL39_RS01000 (NCTC4001_00198) codY 188723..189505 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQL39_RS01005 (NCTC4001_00199) - 189652..190206 (+) 555 WP_002983281.1 cysteine hydrolase family protein -
  DQL39_RS01015 - 190665..190969 (+) 305 Protein_172 putative PEP-binding protein -
  DQL39_RS01020 (NCTC4001_00200) gatC 191201..191503 (+) 303 WP_032467222.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQL39_RS01025 (NCTC4001_00201) gatA 191503..192969 (+) 1467 WP_038433555.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQL39_RS01030 (NCTC4001_00202) gatB 192969..194408 (+) 1440 WP_111718048.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=1019750 DQL39_RS01000 WP_002983278.1 188723..189505(+) (codY) [Streptococcus pyogenes strain NCTC4001]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1019750 DQL39_RS01000 WP_002983278.1 188723..189505(+) (codY) [Streptococcus pyogenes strain NCTC4001]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504