Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQL37_RS07680 Genome accession   NZ_LS483352
Coordinates   1456702..1457484 (-) Length   260 a.a.
NCBI ID   WP_002992569.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12052     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1451702..1462484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL37_RS07650 (NCTC12052_01521) gatB 1451800..1453239 (-) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  DQL37_RS07655 (NCTC12052_01522) gatA 1453239..1454705 (-) 1467 WP_023605256.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQL37_RS07660 (NCTC12052_01523) gatC 1454705..1455007 (-) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQL37_RS07665 - 1455239..1455463 (-) 225 WP_014635660.1 putative PEP-binding protein -
  DQL37_RS07675 (NCTC12052_01524) - 1456001..1456555 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  DQL37_RS07680 (NCTC12052_01525) codY 1456702..1457484 (-) 783 WP_002992569.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQL37_RS07685 (NCTC12052_01526) - 1457701..1458915 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  DQL37_RS07690 (NCTC12052_01527) - 1459146..1459598 (+) 453 WP_002992571.1 universal stress protein -
  DQL37_RS07695 (NCTC12052_01528) - 1459721..1461109 (-) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  DQL37_RS07700 (NCTC12052_01529) - 1461181..1462146 (+) 966 WP_014407795.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28634.75 Da        Isoelectric Point: 4.5065

>NTDB_id=1019714 DQL37_RS07680 WP_002992569.1 1456702..1457484(-) (codY) [Streptococcus pyogenes strain NCTC12052]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDDEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1019714 DQL37_RS07680 WP_002992569.1 1456702..1457484(-) (codY) [Streptococcus pyogenes strain NCTC12052]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACGATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(202-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.765

98.077

0.508