Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQL37_RS00785 Genome accession   NZ_LS483352
Coordinates   117752..118036 (+) Length   94 a.a.
NCBI ID   WP_011284422.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12052     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112752..123036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL37_RS00760 (NCTC12052_00154) - 114698..115063 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL37_RS00765 (NCTC12052_00155) comGA 115156..116094 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL37_RS00770 (NCTC12052_00156) comGB 116030..117064 (+) 1035 WP_225793059.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL37_RS00775 (NCTC12052_00157) comGC 117066..117392 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL37_RS00780 (NCTC12052_00158) comGD 117367..117795 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL37_RS00785 (NCTC12052_00159) comGE 117752..118036 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL37_RS00790 (NCTC12052_00160) comGF 118029..118463 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL37_RS00795 (NCTC12052_00161) comGG 118447..118773 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  DQL37_RS00800 (NCTC12052_00162) comGH 118871..119824 (+) 954 WP_023610092.1 class I SAM-dependent methyltransferase Machinery gene
  DQL37_RS00805 (NCTC12052_00163) - 119883..121079 (+) 1197 WP_002992742.1 acetate kinase -
  DQL37_RS00810 - 121266..121574 (+) 309 WP_032467031.1 hypothetical protein -
  DQL37_RS00815 (NCTC12052_00164) proC 121657..122427 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10654.59 Da        Isoelectric Point: 8.9043

>NTDB_id=1019649 DQL37_RS00785 WP_011284422.1 117752..118036(+) (comGE) [Streptococcus pyogenes strain NCTC12052]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEITLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1019649 DQL37_RS00785 WP_011284422.1 117752..118036(+) (comGE) [Streptococcus pyogenes strain NCTC12052]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATTGCAACAGGCATCCTCTTTAGTATTGT
CATTCTTGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATAACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383