Detailed information NTG1018595

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: DQL34_RS08995
• Genome accession: NZ_LS483339
• Coordinates: 1696150..1696935 (-)
• Length: 261 a.a.
• NCBI ID: WP_084826115.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain NCTC12958
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1691150..1701935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL34_RS08960 (NCTC12958_01891)	gatC	1691216..1691518 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
DQL34_RS08965	-	1691693..1691911 (-)	219	WP_223899686.1	glycosyltransferase	-
DQL34_RS12180	-	1691850..1692014 (-)	165	WP_231838381.1	glycosyltransferase	-
DQL34_RS08975 (NCTC12958_01892)	-	1692451..1693892 (-)	1442	Protein_1705	6-phospho-beta-glucosidase	-
DQL34_RS08980 (NCTC12958_01893)	msrA	1694045..1694554 (-)	510	Protein_1706	peptide-methionine (S)-S-oxide reductase MsrA	-
DQL34_RS08985 (NCTC12958_01894)	-	1694566..1695413 (-)	848	Protein_1707	MetQ/NlpA family ABC transporter substrate-binding protein	-
DQL34_RS08990 (NCTC12958_01895)	-	1695536..1696087 (-)	552	WP_111679685.1	cysteine hydrolase family protein	-
DQL34_RS08995 (NCTC12958_01896)	codY	1696150..1696935 (-)	786	WP_084826115.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
DQL34_RS09000 (NCTC12958_01897)	-	1697195..1698409 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
DQL34_RS09005 (NCTC12958_01898)	-	1698763..1699215 (+)	453	WP_084826116.1	universal stress protein	-
DQL34_RS12185	-	1699391..1699965 (+)	575	Protein_1712	IS30 family transposase	-
DQL34_RS12190 (NCTC12958_01899)	-	1700037..1700645 (-)	609	WP_223899685.1	hypothetical protein	-
DQL34_RS09020 (NCTC12958_01900)	pflA	1700857..1701657 (-)	801	WP_111679686.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28920.07 Da
• Isoelectric Point: 4.4713

>NTDB_id=1018595 DQL34_RS08995 WP_084826115.1 1696150..1696935(-) (codY) [Streptococcus thermophilus strain NCTC12958]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEEFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=1018595 DQL34_RS08995 WP_084826115.1 1696150..1696935(-) (codY) [Streptococcus thermophilus strain NCTC12958]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAGAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACATTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	52.632	94.636	0.498