Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQM35_RS02245 Genome accession   NZ_LS483338
Coordinates   408548..409330 (+) Length   260 a.a.
NCBI ID   WP_002992569.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12064     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 403548..414330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM35_RS02225 (NCTC12064_00438) - 403886..404851 (-) 966 WP_002992573.1 asparaginase -
  DQM35_RS02230 (NCTC12064_00439) - 404923..406311 (+) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  DQM35_RS02235 (NCTC12064_00440) - 406434..406886 (-) 453 WP_002992571.1 universal stress protein -
  DQM35_RS02240 (NCTC12064_00441) - 407117..408331 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  DQM35_RS02245 (NCTC12064_00442) codY 408548..409330 (+) 783 WP_002992569.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQM35_RS02250 (NCTC12064_00443) - 409477..410031 (+) 555 WP_002988559.1 cysteine hydrolase family protein -
  DQM35_RS02260 - 410569..410793 (+) 225 WP_014635660.1 putative PEP-binding protein -
  DQM35_RS02265 (NCTC12064_00444) gatC 411025..411327 (+) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQM35_RS02270 (NCTC12064_00445) gatA 411327..412793 (+) 1467 WP_023605256.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQM35_RS02275 (NCTC12064_00446) gatB 412793..414232 (+) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28634.75 Da        Isoelectric Point: 4.5065

>NTDB_id=1018451 DQM35_RS02245 WP_002992569.1 408548..409330(+) (codY) [Streptococcus pyogenes strain NCTC12064]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDDEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1018451 DQM35_RS02245 WP_002992569.1 408548..409330(+) (codY) [Streptococcus pyogenes strain NCTC12064]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACGATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(202-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.765

98.077

0.508

Multiple sequence alignment