Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQL08_RS00685 Genome accession   NZ_LS483336
Coordinates   104518..104802 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain NCTC12046     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99518..109802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL08_RS00660 (NCTC12046_00132) - 101464..101829 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL08_RS00665 (NCTC12046_00133) comGA 101922..102860 (+) 939 WP_023611500.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL08_RS00670 (NCTC12046_00134) comGB 102796..103830 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL08_RS00675 (NCTC12046_00135) comGC 103832..104158 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL08_RS00680 (NCTC12046_00136) comGD 104133..104561 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL08_RS00685 (NCTC12046_00137) comGE 104518..104802 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL08_RS00690 (NCTC12046_00138) comGF 104795..105229 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL08_RS00695 (NCTC12046_00139) comGG 105213..105539 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL08_RS00700 (NCTC12046_00140) comGH 105637..106590 (+) 954 WP_023611497.1 class I SAM-dependent methyltransferase Machinery gene
  DQL08_RS00705 (NCTC12046_00141) - 106649..107845 (+) 1197 WP_111687938.1 acetate kinase -
  DQL08_RS00710 - 108032..108340 (+) 309 WP_010921804.1 hypothetical protein -
  DQL08_RS00715 (NCTC12046_00142) proC 108423..109193 (-) 771 WP_023611530.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=1018235 DQL08_RS00685 WP_002987779.1 104518..104802(+) (comGE) [Streptococcus pyogenes strain NCTC12046]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1018235 DQL08_RS00685 WP_002987779.1 104518..104802(+) (comGE) [Streptococcus pyogenes strain NCTC12046]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383