Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQL44_RS00685 Genome accession   NZ_LS483335
Coordinates   105635..105919 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain NCTC8332     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 100635..110919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL44_RS00660 (NCTC8332_00133) - 102581..102946 (+) 366 WP_111676997.1 DUF1033 family protein -
  DQL44_RS00665 (NCTC8332_00134) comGA 103039..103977 (+) 939 WP_063812149.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL44_RS00670 (NCTC8332_00135) comGB 103913..104947 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL44_RS00675 (NCTC8332_00136) comGC 104949..105275 (+) 327 WP_111676998.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL44_RS00680 (NCTC8332_00137) comGD 105250..105678 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL44_RS00685 (NCTC8332_00138) comGE 105635..105919 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL44_RS00690 (NCTC8332_00139) comGF 105912..106346 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL44_RS00695 (NCTC8332_00140) comGG 106330..106656 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  DQL44_RS00700 (NCTC8332_00141) comGH 106754..107707 (+) 954 WP_111676999.1 class I SAM-dependent methyltransferase Machinery gene
  DQL44_RS00705 (NCTC8332_00142) - 107766..108962 (+) 1197 WP_020904834.1 acetate kinase -
  DQL44_RS00710 - 109149..109457 (+) 309 WP_111677000.1 hypothetical protein -
  DQL44_RS00715 (NCTC8332_00143) proC 109540..110310 (-) 771 WP_111677001.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=1018136 DQL44_RS00685 WP_002987779.1 105635..105919(+) (comGE) [Streptococcus pyogenes strain NCTC8332]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1018136 DQL44_RS00685 WP_002987779.1 105635..105919(+) (comGE) [Streptococcus pyogenes strain NCTC8332]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAT
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383