Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQL28_RS01960 Genome accession   NZ_LS483334
Coordinates   372074..372856 (+) Length   260 a.a.
NCBI ID   WP_038434236.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12050     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 367074..377856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL28_RS01940 (NCTC12050_00378) - 367411..368376 (-) 966 WP_023078713.1 asparaginase -
  DQL28_RS01945 (NCTC12050_00379) - 368448..369836 (+) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  DQL28_RS01950 (NCTC12050_00380) - 369959..370411 (-) 453 WP_002983265.1 universal stress protein -
  DQL28_RS01955 (NCTC12050_00381) - 370642..371856 (+) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  DQL28_RS01960 (NCTC12050_00382) codY 372074..372856 (+) 783 WP_038434236.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQL28_RS01965 (NCTC12050_00383) - 373003..373557 (+) 555 WP_002992568.1 cysteine hydrolase family protein -
  DQL28_RS01975 (NCTC12050_00384) - 374016..374336 (+) 321 Protein_328 putative PEP-binding protein -
  DQL28_RS01980 (NCTC12050_00385) gatC 374568..374870 (+) 303 WP_111676172.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQL28_RS01985 (NCTC12050_00386) gatA 374870..376336 (+) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQL28_RS01990 (NCTC12050_00387) gatB 376336..377775 (+) 1440 WP_023078673.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28647.79 Da        Isoelectric Point: 4.5611

>NTDB_id=1018059 DQL28_RS01960 WP_038434236.1 372074..372856(+) (codY) [Streptococcus pyogenes strain NCTC12050]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPIESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1018059 DQL28_RS01960 WP_038434236.1 372074..372856(+) (codY) [Streptococcus pyogenes strain NCTC12050]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTATTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

50.98

98.077

0.5