Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQL30_RS02130 Genome accession   NZ_LS483333
Coordinates   395916..396698 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain NCTC12048     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 390916..401698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL30_RS02110 (NCTC12048_00418) - 391253..392218 (-) 966 WP_002983258.1 asparaginase -
  DQL30_RS02115 (NCTC12048_00419) - 392290..393678 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  DQL30_RS02120 (NCTC12048_00420) - 393801..394253 (-) 453 WP_002983265.1 universal stress protein -
  DQL30_RS02125 (NCTC12048_00421) - 394484..395698 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  DQL30_RS02130 (NCTC12048_00422) codY 395916..396698 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQL30_RS02135 (NCTC12048_00423) - 396845..397399 (+) 555 WP_002983281.1 cysteine hydrolase family protein -
  DQL30_RS02145 (NCTC12048_00424) - 397858..398178 (+) 321 Protein_363 putative PEP-binding protein -
  DQL30_RS02150 (NCTC12048_00425) gatC 398410..398712 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQL30_RS02155 (NCTC12048_00426) gatA 398712..400178 (+) 1467 WP_053308228.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQL30_RS02160 (NCTC12048_00427) gatB 400178..401617 (+) 1440 WP_111713629.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=1017965 DQL30_RS02130 WP_002983278.1 395916..396698(+) (codY) [Streptococcus pyogenes strain NCTC12048]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1017965 DQL30_RS02130 WP_002983278.1 395916..396698(+) (codY) [Streptococcus pyogenes strain NCTC12048]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment