Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQL59_RS07395 Genome accession   NZ_LS483326
Coordinates   1462836..1463120 (-) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain NCTC12045     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1457836..1468120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL59_RS07365 (NCTC12045_01458) proC 1458445..1459215 (+) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -
  DQL59_RS07370 - 1459298..1459606 (-) 309 WP_041174321.1 hypothetical protein -
  DQL59_RS07375 (NCTC12045_01459) - 1459793..1460989 (-) 1197 WP_111681328.1 acetate kinase -
  DQL59_RS07380 (NCTC12045_01460) comGH 1461048..1462001 (-) 954 WP_111681329.1 class I SAM-dependent methyltransferase Machinery gene
  DQL59_RS07385 (NCTC12045_01461) comGG 1462099..1462425 (-) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL59_RS07390 (NCTC12045_01462) comGF 1462409..1462843 (-) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL59_RS07395 (NCTC12045_01463) comGE 1462836..1463120 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL59_RS07400 (NCTC12045_01464) comGD 1463077..1463505 (-) 429 WP_111681330.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL59_RS07405 (NCTC12045_01465) comGC 1463480..1463806 (-) 327 WP_111681331.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL59_RS07410 (NCTC12045_01466) comGB 1463808..1464842 (-) 1035 WP_227874808.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL59_RS07415 (NCTC12045_01467) comGA 1464778..1465716 (-) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL59_RS07420 (NCTC12045_01468) - 1465809..1466174 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=1017423 DQL59_RS07395 WP_002987779.1 1462836..1463120(-) (comGE) [Streptococcus pyogenes strain NCTC12045]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1017423 DQL59_RS07395 WP_002987779.1 1462836..1463120(-) (comGE) [Streptococcus pyogenes strain NCTC12045]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTGAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383