Detailed information NTG1016954

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: DQL31_RS08415
• Genome accession: NZ_LS483320
• Coordinates: 1587326..1589665 (-)
• Length: 779 a.a.
• NCBI ID: WP_111677464.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC5164
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1582326..1594665

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL31_RS08375 (NCTC5164_01684)	rpsR	1582711..1582950 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
DQL31_RS08380 (NCTC5164_01685)	ssbA	1583115..1583606 (-)	492	WP_111677461.1	single-stranded DNA-binding protein	Machinery gene
DQL31_RS08385 (NCTC5164_01686)	rpsF	1583628..1583918 (-)	291	WP_063632424.1	30S ribosomal protein S6	-
DQL31_RS08390 (NCTC5164_01687)	-	1584091..1584384 (-)	294	WP_002983113.1	hypothetical protein	-
DQL31_RS08395 (NCTC5164_01688)	mutY	1584552..1585706 (+)	1155	WP_002988276.1	A/G-specific adenine glycosylase	-
DQL31_RS08400 (NCTC5164_01689)	-	1585782..1586375 (+)	594	WP_111677462.1	helix-turn-helix domain-containing protein	-
DQL31_RS08405 (NCTC5164_01690)	trxA	1586427..1586759 (-)	333	WP_001932060.1	thioredoxin	-
DQL31_RS08410 (NCTC5164_01691)	-	1586822..1587322 (-)	501	WP_172448848.1	phosphatase PAP2 family protein	-
DQL31_RS08415 (NCTC5164_01692)	mutS/mutS2	1587326..1589665 (-)	2340	WP_111677464.1	endonuclease MutS2	Machinery gene
DQL31_RS08420 (NCTC5164_01693)	-	1589814..1590359 (-)	546	WP_002983087.1	CvpA family protein	-
DQL31_RS08425 (NCTC5164_01694)	-	1590362..1590670 (-)	309	WP_002993251.1	hypothetical protein	-
DQL31_RS08430 (NCTC5164_01695)	rnhC	1590827..1591729 (+)	903	WP_002988245.1	ribonuclease HIII	-
DQL31_RS08435 (NCTC5164_01696)	lepB	1591740..1592333 (+)	594	WP_002983074.1	signal peptidase I	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87754.91 Da
• Isoelectric Point: 6.3839

>NTDB_id=1016954 DQL31_RS08415 WP_111677464.1 1587326..1589665(-) (mutS/mutS2) [Streptococcus pyogenes strain NCTC5164]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRSQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=1016954 DQL31_RS08415 WP_111677464.1 1587326..1589665(-) (mutS/mutS2) [Streptococcus pyogenes strain NCTC5164]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTAGTCAATTAACAAAC
AGTGAACGACGGGTTCGTCAGATTTTACAAGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGT
CATGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATCTCTGATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGCTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTGGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCCGAAACGCTTAGCCCCACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGATCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (324-505)

• Smr domain (Smr) (704-778)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-669)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.633	100	0.412