Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   DQL11_RS01775 Genome accession   NZ_LS483315
Coordinates   327204..329543 (+) Length   779 a.a.
NCBI ID   WP_111704532.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12059     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 322204..334543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL11_RS01755 (NCTC12059_00348) lepB 324536..325129 (-) 594 WP_002983074.1 signal peptidase I -
  DQL11_RS01760 (NCTC12059_00349) rnhC 325140..326042 (-) 903 WP_020905449.1 ribonuclease HIII -
  DQL11_RS01765 (NCTC12059_00350) - 326199..326507 (+) 309 WP_002993251.1 hypothetical protein -
  DQL11_RS01770 (NCTC12059_00351) - 326510..327055 (+) 546 WP_002993250.1 CvpA family protein -
  DQL11_RS01775 (NCTC12059_00352) mutS/mutS2 327204..329543 (+) 2340 WP_111704532.1 endonuclease MutS2 Machinery gene
  DQL11_RS01780 (NCTC12059_00353) - 329547..330047 (+) 501 WP_030126907.1 phosphatase PAP2 family protein -
  DQL11_RS01785 (NCTC12059_00354) trxA 330110..330442 (+) 333 WP_001932060.1 thioredoxin -
  DQL11_RS01790 (NCTC12059_00355) - 330488..331075 (-) 588 WP_111704533.1 helix-turn-helix domain-containing protein -
  DQL11_RS01795 (NCTC12059_00356) mutY 331261..332406 (-) 1146 WP_331773754.1 A/G-specific adenine glycosylase -
  DQL11_RS01800 (NCTC12059_00357) - 332574..332867 (+) 294 WP_002983113.1 hypothetical protein -
  DQL11_RS01805 (NCTC12059_00358) rpsF 333040..333330 (+) 291 WP_002983117.1 30S ribosomal protein S6 -
  DQL11_RS01810 (NCTC12059_00359) ssb 333352..333843 (+) 492 WP_002983122.1 single-stranded DNA-binding protein Machinery gene
  DQL11_RS01815 (NCTC12059_00360) rpsR 334008..334247 (+) 240 WP_002983142.1 30S ribosomal protein S18 -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87860.10 Da        Isoelectric Point: 6.5500

>NTDB_id=1016436 DQL11_RS01775 WP_111704532.1 327204..329543(+) (mutS/mutS2) [Streptococcus pyogenes strain NCTC12059]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSEMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=1016436 DQL11_RS01775 WP_111704532.1 327204..329543(+) (mutS/mutS2) [Streptococcus pyogenes strain NCTC12059]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGAGATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAAAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTTTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAAACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGTCCTACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAGCGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCGCCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCTCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGGATTGGTACAGGCGTTATCCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGCGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(704-778)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.633

100

0.412