Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DQL09_RS08185 Genome accession   NZ_LS483307
Coordinates   1533374..1534156 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain NCTC5163     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1528374..1539156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL09_RS08155 (NCTC5163_01643) gatB 1528472..1529911 (-) 1440 WP_111677444.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  DQL09_RS08160 (NCTC5163_01644) gatA 1529911..1531377 (-) 1467 WP_111677445.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  DQL09_RS08165 (NCTC5163_01645) gatC 1531377..1531679 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  DQL09_RS08170 - 1531911..1532135 (-) 225 WP_227874710.1 putative PEP-binding protein -
  DQL09_RS08180 - 1532673..1533227 (-) 555 Protein_1547 cysteine hydrolase family protein -
  DQL09_RS08185 (NCTC5163_01648) codY 1533374..1534156 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DQL09_RS08190 (NCTC5163_01649) - 1534374..1535588 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  DQL09_RS08195 (NCTC5163_01650) - 1535818..1536270 (+) 453 WP_002992571.1 universal stress protein -
  DQL09_RS08200 (NCTC5163_01651) - 1536393..1537781 (-) 1389 WP_111677447.1 Cof-type HAD-IIB family hydrolase -
  DQL09_RS08205 (NCTC5163_01652) - 1537853..1538818 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=1016035 DQL09_RS08185 WP_002983278.1 1533374..1534156(-) (codY) [Streptococcus pyogenes strain NCTC5163]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1016035 DQL09_RS08185 WP_002983278.1 1533374..1534156(-) (codY) [Streptococcus pyogenes strain NCTC5163]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTTATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504