Detailed information NTG1012131

Bioinformatically predicted

Overview

• Name: recD/recD2/recDB
• Type: Machinery gene
• Locus tag: H1W81_RS02530
• Genome accession: NZ_LR824002
• Coordinates: 459546..462050 (-)
• Length: 834 a.a.
• NCBI ID: WP_011226558.1
• Uniprot ID: Q5M2P0
• Organism: Streptococcus thermophilus isolate STH_CIRM_67
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 454546..467050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W81_RS02500 (STHERMO_0525)	-	455825..456055 (-)	231	WP_002947111.1	DNA-dependent RNA polymerase subunit epsilon	-
H1W81_RS02505 (STHERMO_0526)	tsaB	456319..457005 (+)	687	WP_002947108.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	-
H1W81_RS02510 (STHERMO_0527)	rimI	457007..457420 (+)	414	WP_014621963.1	ribosomal protein S18-alanine N-acetyltransferase	-
H1W81_RS02515 (STHERMO_0528)	tsaD	457420..458433 (+)	1014	WP_002951922.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
H1W81_RS02520 (STHERMO_0529)	-	458479..459177 (+)	699	WP_011226560.1	AzlC family ABC transporter permease	-
H1W81_RS02525 (STHERMO_0530)	-	459164..459490 (+)	327	WP_011226559.1	AzlD domain-containing protein	-
H1W81_RS02530 (STHERMO_0531)	recD/recD2/recDB	459546..462050 (-)	2505	WP_011226558.1	ATP-dependent RecD-like DNA helicase	Machinery gene
H1W81_RS02535 (STHERMO_0532)	lepB	462112..462735 (-)	624	WP_002947854.1	signal peptidase I	-
H1W81_RS02540 (STHERMO_0533)	rnhC	462754..463644 (-)	891	WP_011226557.1	ribonuclease HIII	-
H1W81_RS02545 (STHERMO_0534)	-	463958..464275 (+)	318	WP_002947863.1	hypothetical protein	-
H1W81_RS02550 (STHERMO_0535)	-	464272..464814 (+)	543	WP_011226556.1	CvpA family protein	-

Sequence

Protein

• Length: 834 a.a.
• Molecular weight: 94209.60 Da
• Isoelectric Point: 4.5917

>NTDB_id=1012131 H1W81_RS02530 WP_011226558.1 459546..462050(-) (recD/recD2/recDB) [Streptococcus thermophilus isolate STH_CIRM_67]
MQEFYFSGTIERIIFENASNFFRILLLEIDETDSDFEDYEIIVTGTMGDVMEGEDYTFWGQLTNHPKYGKQLQMTRYERS
KPSASGLIKYFSSDNFKGIGKKTAERIVEIYGEDPIDKILEDPSKLEQIPNLSKVNREAFLAKLKINYGTEQILSKLSSY
GLTPKAASQIFNQYKEESLNLIEKYPYLLVEEVQGIGFKMADQLAERLGIASDAPERLRAALIHCLLEASMEEGDTYIEA
KSLLERTIILLESSRQIELDPALVAHQLTNLIQEDKVQNIETKIFDNTLYFAEQGIYTHLTRITKDQPDISAEDKIQASL
ERVEDELGITYDKVQKDAIIKALQSKVFILTGGPGTGKTTVINGIIKTYADLHGLDLKKSDLPIILAAPTGRAARRMNEL
TKLPSATIHRHLGLNGEDDFKTLDDYLDCDLIIIDEFSMVDTWLANQLFESISDTTQVIIVGDQDQLPSVGPGQVLADLL
QIDDLPKVSLTKIFRQSEDSTIVTLASQIRQGQLPTDFTEKKADRSYFEANANHIPQMVPKIVSAAIKSGIAAQDVQILA
PMYRGQAGINNLNTIMQDLLNPKEKANQFAFNDIFFRKNDKILHLVNDTELNVFNGDIGIITDLIPGKYTESKQDEIYMS
FDGNEVIYPRNEWNKITLAYAMSIHKSQGSEFPVVILPITRQSGRMLQRNLIYTAITRAKSKLVMLGEIAAFDYAVHNEG
AKRNTYLIQRFEQTYTQAVDKSVEKNVKNEGTDAFNQTKTENNRPSETLENKDFSENINPSQTLINTYSHPVDKSVNKPV
QTEENYRLTEENWATIDPMIGLSEDDIAAFFNNN

Nucleotide

• Length: 2505 bp

>NTDB_id=1012131 H1W81_RS02530 WP_011226558.1 459546..462050(-) (recD/recD2/recDB) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGCAAGAATTTTATTTTTCAGGAACTATCGAGCGCATCATTTTTGAAAATGCCAGTAATTTTTTTCGTATCCTACTCTT
AGAAATTGATGAAACTGACAGTGATTTTGAAGACTATGAAATCATTGTTACTGGAACTATGGGGGATGTCATGGAGGGGG
AAGACTATACCTTCTGGGGTCAGCTAACCAATCACCCCAAATATGGCAAACAACTCCAAATGACTCGCTACGAGCGTTCA
AAACCCTCTGCCAGTGGCCTTATCAAATATTTCTCCAGTGATAATTTCAAAGGAATCGGTAAGAAAACGGCCGAGCGTAT
TGTCGAGATTTATGGCGAAGACCCTATTGACAAGATTCTCGAAGACCCTAGTAAATTAGAGCAGATTCCTAATCTGTCCA
AGGTAAACCGAGAAGCCTTCCTTGCAAAATTAAAAATCAACTATGGTACTGAACAAATCTTGTCCAAACTTTCCAGCTAT
GGACTCACACCAAAGGCTGCCTCACAAATTTTCAACCAATATAAGGAAGAATCACTTAACCTTATCGAAAAATATCCTTA
TCTCTTGGTAGAGGAAGTCCAGGGAATTGGATTTAAAATGGCCGATCAACTAGCCGAACGCCTAGGGATTGCTAGCGATG
CTCCTGAGCGTTTACGAGCCGCCCTAATTCACTGTCTGCTAGAAGCTAGTATGGAAGAAGGGGACACCTACATCGAAGCC
AAGTCCTTGCTTGAACGGACTATCATTCTTTTGGAAAGTTCTCGCCAGATTGAACTTGACCCTGCCTTGGTTGCTCACCA
ATTGACCAACCTCATCCAAGAGGATAAGGTGCAAAATATAGAGACTAAAATTTTTGATAATACCCTATATTTTGCAGAAC
AGGGCATCTATACCCACCTAACTCGTATCACGAAAGACCAGCCTGACATCAGTGCTGAGGACAAAATCCAAGCAAGTCTT
GAAAGGGTGGAAGATGAGCTTGGTATCACCTATGACAAGGTTCAAAAAGATGCCATTATTAAAGCCCTACAAAGCAAGGT
CTTCATCCTGACAGGTGGTCCCGGAACAGGAAAAACCACTGTTATTAACGGAATTATTAAAACCTATGCTGACCTTCATG
GTTTAGACCTCAAAAAGTCTGATTTACCCATTATTTTAGCAGCGCCAACGGGACGGGCTGCTCGTCGGATGAACGAACTG
ACCAAGCTTCCTAGTGCCACTATCCATAGACATTTGGGGCTTAATGGCGAGGACGATTTCAAGACCTTAGATGACTATCT
TGATTGCGATTTGATTATCATCGATGAGTTCTCTATGGTTGATACTTGGTTGGCCAATCAACTCTTCGAAAGCATTTCCG
ATACTACTCAAGTAATCATTGTAGGTGACCAAGATCAGCTACCTTCTGTAGGCCCTGGCCAAGTCTTAGCTGACCTTTTG
CAGATTGATGACTTGCCTAAGGTTTCCCTAACCAAAATTTTCAGACAATCTGAGGATTCCACTATTGTTACCTTAGCTAG
CCAGATACGCCAAGGCCAACTACCCACTGATTTCACAGAGAAAAAAGCTGACCGATCATACTTTGAGGCTAATGCTAACC
ATATTCCACAGATGGTCCCTAAAATTGTCTCTGCCGCTATTAAAAGTGGGATCGCTGCTCAGGATGTACAGATTCTGGCC
CCCATGTACCGGGGACAGGCTGGTATCAACAATCTCAATACCATTATGCAGGATCTACTTAATCCCAAAGAAAAAGCCAA
TCAATTTGCCTTTAATGATATTTTCTTCCGTAAGAATGACAAGATTCTCCACCTGGTCAACGATACAGAACTCAATGTCT
TCAATGGCGATATCGGAATCATTACTGATCTCATACCTGGTAAATATACTGAAAGTAAGCAAGACGAAATTTACATGTCC
TTCGATGGCAATGAGGTTATCTATCCTCGTAACGAATGGAATAAGATTACTCTGGCCTATGCCATGTCTATACACAAATC
CCAAGGGAGTGAATTCCCAGTCGTTATCCTTCCCATCACACGCCAAAGTGGGCGTATGCTTCAACGTAACCTCATCTACA
CTGCTATCACACGCGCCAAGAGTAAACTGGTCATGTTGGGGGAAATCGCAGCCTTCGATTATGCCGTTCACAACGAGGGG
GCCAAACGTAATACCTACCTCATCCAACGTTTTGAACAAACTTATACACAAGCTGTTGATAAGTCTGTCGAAAAGAATGT
TAAAAACGAGGGAACAGACGCCTTCAATCAAACAAAAACGGAAAACAATAGACCCTCAGAAACCCTTGAAAACAAAGACT
TCTCGGAAAATATCAATCCATCCCAAACTCTTATTAACACTTATTCACATCCTGTGGATAAGTCTGTTAACAAACCTGTG
CAAACAGAAGAAAACTATCGTTTAACTGAAGAAAACTGGGCAACTATCGACCCAATGATAGGTCTCAGCGAAGACGATAT
TGCAGCCTTTTTTAACAACAACTAG

Domains

Predicted by InterProScan.

• UvrD-like helicase C-terminal domain (UvrD_C_2) (659-705)

• AAA domain (AAA_30) (331-524)

• Helix-hairpin-helix containing domain (HHH_RecD2) (147-237)

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (572-638)

3D structure

• AlphaFold DB: Q5M2P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD/recD2/recDB	Bacillus subtilis subsp. subtilis str. 168	44.712	89.568	0.4