Detailed information NTG1011791

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: H1W86_RS07500
• Genome accession: NZ_LR822042
• Coordinates: 1449891..1450676 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus isolate STH_CIRM_1358
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1444891..1455676

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W86_RS07465 (STHERMO_1642)	gatC	1444953..1445255 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
H1W86_RS07470	-	1445395..1445649 (-)	255	WP_024010053.1	glycosyl transferase	-
H1W86_RS07475 (STHERMO_1644)	-	1445662..1445871 (-)	210	WP_080998437.1	glycosyltransferase	-
H1W86_RS07480	-	1446187..1447631 (-)	1445	Protein_1437	6-phospho-beta-glucosidase	-
H1W86_RS07485 (STHERMO_1647)	msrA	1447784..1448293 (-)	510	WP_041827375.1	peptide-methionine (S)-S-oxide reductase MsrA	-
H1W86_RS07490 (STHERMO_1648)	-	1448305..1449153 (-)	849	WP_014608646.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
H1W86_RS07495 (STHERMO_1649)	-	1449277..1449828 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
H1W86_RS07500 (STHERMO_1650)	codY	1449891..1450676 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
H1W86_RS07505 (STHERMO_1651)	-	1450936..1452150 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
H1W86_RS07510 (STHERMO_1652)	-	1452505..1452957 (+)	453	WP_002946987.1	universal stress protein	-
H1W86_RS09815	-	1453137..1453708 (+)	572	Protein_1444	IS30 family transposase	-
H1W86_RS09820 (STHERMO_1655)	-	1453780..1454376 (-)	597	WP_232086461.1	hypothetical protein	-
H1W86_RS07520 (STHERMO_1657)	pflA	1454588..1455388 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=1011791 H1W86_RS07500 WP_002951720.1 1449891..1450676(-) (codY) [Streptococcus thermophilus isolate STH_CIRM_1358]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=1011791 H1W86_RS07500 WP_002951720.1 1449891..1450676(-) (codY) [Streptococcus thermophilus isolate STH_CIRM_1358]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502