Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   H1W94_RS08195 Genome accession   NZ_LR822041
Coordinates   1584447..1586798 (+) Length   783 a.a.
NCBI ID   WP_011227556.1    Uniprot ID   Q5LY40
Organism   Streptococcus thermophilus isolate STH_CIRM_1122     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1579447..1591798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W94_RS08175 (STHERMO_1821) - 1580099..1580350 (-) 252 WP_011227553.1 hypothetical protein -
  H1W94_RS08180 (STHERMO_1822) - 1580453..1580665 (-) 213 WP_011226552.1 hypothetical protein -
  H1W94_RS08185 (STHERMO_1823) - 1580668..1580982 (-) 315 WP_231108732.1 hypothetical protein -
  H1W94_RS08190 (STHERMO_1825) polA 1581601..1584240 (-) 2640 WP_011227555.1 DNA polymerase I -
  H1W94_RS08195 (STHERMO_1826) mutS/mutS2 1584447..1586798 (+) 2352 WP_011227556.1 endonuclease MutS2 Machinery gene
  H1W94_RS08200 (STHERMO_1827) - 1586899..1587441 (-) 543 WP_011227557.1 CvpA family protein -
  H1W94_RS08205 (STHERMO_1828) - 1587438..1587755 (-) 318 WP_002947863.1 hypothetical protein -
  H1W94_RS08210 (STHERMO_1829) rnhC 1588069..1588959 (+) 891 WP_011227558.1 ribonuclease HIII -
  H1W94_RS08215 (STHERMO_1830) lepB 1588978..1589601 (+) 624 WP_002947854.1 signal peptidase I -

Sequence

Protein


Download         Length: 783 a.a.        Molecular weight: 88024.39 Da        Isoelectric Point: 6.5519

>NTDB_id=1011699 H1W94_RS08195 WP_011227556.1 1584447..1586798(+) (mutS/mutS2) [Streptococcus thermophilus isolate STH_CIRM_1122]
MNTKILDQLEFNKVKDQFTEYLQTEQAQAELCDLVPMTNPERIQNQFTEIQEMSEIFVEHHGFAIGSLRDISEPLRRLEL
DADLNIQELIAIKKVLQASADLSRFYADLENVELIALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKA
CDDAIRQTLQDILKKSGHMLAENLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEKITQLRADER
HEMARILHELSDQLRPHTAAIANNAWILGHMDFIRGKYLYLHDKKAIIPEISDNQTLQLLNVRHPLLINPVANDLRFDED
LTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRVAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILNTAD
SNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLRPTYRFMQGVPG
RSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLEAQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKE
LEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGKLKKLAAQVDLSKNKVLRKAKKEKAARAPRVGDDIIVT
AYGQRGTLTSQAKNGNWEAQVGLIKMSLKADEFTLVRTQAEAQQPKKKQINVVKKAKKTSSDGPRARLDLRGKRYEEAMQ
ELDAFIDQALLNNMSQVEIIHGIGTGVIRDAVTKYLRRHRHVKNFEYAPQSAGGSGCTIATLG

Nucleotide


Download         Length: 2352 bp        

>NTDB_id=1011699 H1W94_RS08195 WP_011227556.1 1584447..1586798(+) (mutS/mutS2) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGAACACAAAGATTTTAGACCAATTAGAATTTAACAAGGTCAAAGACCAGTTCACAGAATACCTGCAGACCGAACAGGC
TCAGGCGGAGTTATGTGACTTGGTGCCTATGACCAATCCAGAAAGAATTCAAAACCAATTTACAGAAATCCAAGAAATGT
CTGAGATTTTCGTAGAGCATCATGGCTTTGCCATTGGTAGCTTAAGAGATATTTCTGAGCCCTTGCGTCGCTTGGAACTG
GATGCTGACCTCAACATCCAGGAGCTCATTGCTATCAAGAAGGTCTTGCAAGCTTCAGCTGACCTTAGCCGCTTCTACGC
TGACCTTGAAAATGTTGAACTCATCGCTCTTAAACGTCTTTTTGAAAAGATTGAGGCCTTTCCAAGTCTACAAGGTAGTC
TTCAAAGTATAAATGATGGTGGTTTTATTGAGCATTTTGCTAGTCCTGAGTTGCAAAATATCCGTCGTCAACTTAAGGCT
TGTGATGATGCCATTCGCCAGACCTTGCAAGACATTCTCAAGAAATCTGGGCACATGTTAGCTGAGAACTTAATTGCTAG
TCGTAATGGCCGTTCAGTGCTTCCTGTCAAAAATACCTACCGTAACCGTATTGCGGGGGTTGTTCATGACATCTCAAGCT
CTGGGAACACAGTGTATATCGAGCCACGAGCCGTTATCCAGCTTAACGAAAAAATTACACAATTACGTGCAGACGAGCGC
CATGAGATGGCACGTATCCTACATGAACTGTCTGATCAACTCCGTCCACATACTGCTGCCATCGCTAACAACGCTTGGAT
TTTGGGCCATATGGACTTCATTAGAGGAAAATACCTCTATCTCCATGATAAAAAGGCAATTATTCCAGAGATTAGTGACA
ACCAAACACTCCAACTGCTTAACGTTCGTCACCCTCTTTTAATCAATCCAGTAGCCAACGATTTGCGCTTTGATGAGGAT
CTCACGGTCATTGTCATTACAGGTCCCAATACTGGTGGTAAAACGGTCATGCTTAAAACTCTAGGACTAGCTCAACTAAT
GGCTCAATCTGGTCTGCCAATTTTGGCTGATAAGGGCAGTCGTGTAGCCATTTTCCAAGAGATTTTTGCGGATATCGGAG
ACGAACAGTCTATCGAACAGAGCTTGTCAACTTTCTCTAGTCACATGACGCACATTGTCGAGATTTTGAACACTGCCGAC
AGCAATAGCTTGGTCTTGGTCGATGAGCTTGGGGCTGGTACCGACCCTCAGGAAGGGGCTAGTCTAGCCATGGCAATCCT
AGAGCACCTCCGTTTGAGCCAGATTAAGACCATGGCTACTACTCACTATCCTGAGCTTAAGGCCTATGGGATTGAGACAC
AACATGTGGAAAATGCTAGCATGGAGTTTGACACAGCAACTCTAAGACCTACCTATCGCTTTATGCAAGGGGTTCCTGGT
CGCTCTAACGCCTTTGAGATTGCTCGCCGCCTCGGTTTGAATGAGATTATTGTCAAGGAAGCAGAAAACCTCACTGATAC
GGATAGTGATGTCAACCGTATCATCGAGCAACTTGAAGCCCAAACTGTAGAAACACAAAAACGTCTGGAGCACATCAAGG
ACGTTGAGCAAGAGAACCTTAAATTCAACCGTGCGGTCAAGAAACTCTATAATGAATTCTCCCATGAGTACGACAAGGAA
CTCGAAAAGGCTCAAAAAGAAATTCAAGAGATGGTGGATACAGCTTTAGCTGAAAGCGATAGTATTCTCAAAAATCTCCA
TGATAAGAGTCAACTCAAGCCTCATGAAGTTATCGACGCCAAAGGGAAACTTAAGAAACTTGCCGCACAAGTCGACCTTT
CTAAGAACAAGGTTCTTCGTAAAGCCAAGAAAGAAAAGGCTGCGCGTGCCCCTCGTGTCGGTGATGATATCATCGTTACT
GCCTATGGGCAACGTGGTACGCTCACCAGTCAAGCCAAAAATGGTAACTGGGAAGCTCAAGTGGGTCTCATCAAGATGAG
CCTAAAGGCAGACGAATTCACTCTGGTTCGTACCCAAGCAGAAGCACAACAACCCAAGAAAAAACAAATTAATGTGGTTA
AAAAAGCCAAGAAGACATCTTCTGATGGGCCTCGTGCCCGTCTAGACCTTCGTGGGAAACGTTACGAAGAAGCCATGCAA
GAGCTCGATGCCTTTATTGACCAAGCTCTACTTAACAACATGAGTCAGGTGGAAATCATCCACGGTATTGGTACCGGTGT
CATCCGAGATGCTGTAACCAAATATCTCCGCCGTCATCGCCATGTTAAAAATTTTGAATATGCCCCACAAAGTGCTGGTG
GTTCCGGATGTACCATCGCAACCTTGGGTTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(708-782)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-672)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5LY40

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.295

100

0.398