Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   H1W74_RS07980 Genome accession   NZ_LR822031
Coordinates   1557661..1560012 (+) Length   783 a.a.
NCBI ID   WP_002947868.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1552661..1565012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS07955 (STHERMO_1813) - 1553270..1553590 (-) 321 WP_002947878.1 hypothetical protein -
  H1W74_RS07960 (STHERMO_1814) - 1553723..1553950 (-) 228 WP_042798944.1 hypothetical protein -
  H1W74_RS07965 (STHERMO_1815) - 1553937..1554113 (-) 177 WP_022096698.1 hypothetical protein -
  H1W74_RS07970 (STHERMO_1816) - 1554114..1554398 (-) 285 WP_002947874.1 hypothetical protein -
  H1W74_RS07975 (STHERMO_1817) polA 1554815..1557454 (-) 2640 WP_002947871.1 DNA polymerase I -
  H1W74_RS07980 (STHERMO_1818) mutS/mutS2 1557661..1560012 (+) 2352 WP_002947868.1 endonuclease MutS2 Machinery gene
  H1W74_RS07985 (STHERMO_1819) - 1560113..1560655 (-) 543 WP_002947866.1 CvpA family protein -
  H1W74_RS07990 (STHERMO_1820) - 1560652..1560969 (-) 318 WP_002947863.1 hypothetical protein -
  H1W74_RS07995 (STHERMO_1821) rnhC 1561283..1562173 (+) 891 WP_022096699.1 ribonuclease HIII -
  H1W74_RS08000 (STHERMO_1822) lepB 1562192..1562815 (+) 624 WP_002947854.1 signal peptidase I -

Sequence

Protein


Download         Length: 783 a.a.        Molecular weight: 88107.47 Da        Isoelectric Point: 6.6236

>NTDB_id=1010754 H1W74_RS07980 WP_002947868.1 1557661..1560012(+) (mutS/mutS2) [Streptococcus thermophilus isolate STH_CIRM_1047]
MNTKILDQLEFNKVKDQFTEYLQTEQAQAELRDLVPMTNPERIQNQFTEIQEMSEIFVEHHGFAIGSLRDISEPLRRLEL
DADLNIQELIAIKKVLQASADLSRFYADLENVELIALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKA
CDDAIRQTLQDILKKSGHMLAENLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEKITQLRADER
HEMARILHELSDQLRPHTAAIANNAWILGHMDFIRGKYLYLHDKKAIIPEISDNQTLQLLNVRHPLLINPVANDLRFDED
LTVIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRVAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILNTAD
SNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLRPTYRFMQGVPG
RSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLEAQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKE
LEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGKLKKLAAQVDLSKNKVLRKAKKEKATRAPRVGDDIIVT
AYGQRGTLTSQAKNGNWEAQVGLIKMSLKADEFTLVRTQAEAQQPKKKQINVVKKAKKTSSDGPRARLDLRGKRYEEAMQ
ELDAFIDQALLNNMSQVEIIHGIGTGVIRDAVTKYLRRHRHVKNFEYAPQSAGGSGCTIATLG

Nucleotide


Download         Length: 2352 bp        

>NTDB_id=1010754 H1W74_RS07980 WP_002947868.1 1557661..1560012(+) (mutS/mutS2) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGAACACAAAGATTTTAGACCAATTAGAATTTAACAAGGTCAAAGACCAGTTCACAGAATACCTGCAGACCGAACAGGC
TCAGGCGGAGTTACGTGACTTGGTGCCTATGACCAATCCAGAAAGAATTCAAAACCAATTTACAGAAATCCAAGAAATGT
CTGAGATTTTCGTAGAGCATCATGGCTTTGCCATTGGTAGCTTAAGAGATATTTCTGAGCCCTTGCGTCGCTTGGAACTG
GATGCTGACCTCAACATCCAGGAGCTCATTGCTATCAAGAAGGTCTTGCAAGCTTCAGCTGACCTTAGCCGCTTCTACGC
TGACCTTGAAAATGTTGAACTCATCGCTCTTAAACGTCTTTTTGAAAAGATTGAGGCCTTTCCAAGTCTACAAGGTAGTC
TTCAAAGTATTAATGATGGTGGTTTTATTGAGCATTTTGCTAGTCCTGAGTTGCAAAATATCCGTCGTCAACTTAAGGCT
TGTGATGATGCCATTCGCCAGACCTTGCAAGACATTCTCAAGAAATCTGGGCACATGTTAGCTGAGAACTTAATTGCTAG
TCGTAATGGCCGTTCAGTGCTTCCTGTCAAAAATACCTACCGTAACCGTATTGCGGGGGTTGTTCATGACATCTCAAGCT
CTGGGAACACAGTGTATATCGAGCCACGAGCCGTTATCCAGCTTAACGAAAAAATTACACAATTACGTGCAGACGAGCGC
CATGAGATGGCACGTATCCTACATGAACTGTCTGATCAACTCCGTCCACATACTGCTGCCATCGCTAACAACGCTTGGAT
TTTGGGCCATATGGACTTCATTAGAGGAAAATACCTCTATCTCCATGATAAAAAGGCAATTATTCCAGAGATTAGTGACA
ACCAAACACTCCAACTGCTTAACGTTCGTCACCCTCTTTTAATCAATCCAGTAGCCAACGATTTGCGCTTTGATGAGGAT
CTCACGGTCATTGTCATTACAGGTCCCAATACTGGTGGTAAAACGGTCATGCTTAAAACTCTAGGACTAGCTCAACTAAT
GGCTCAATCTGGTCTGCCAATTTTGGCTGATAAGGGCAGTCGTGTAGCCATTTTCCAAGAGATTTTTGCGGATATCGGAG
ACGAACAGTCTATCGAACAGAGCTTGTCAACTTTCTCTAGTCACATGACGCACATTGTCGAGATTTTGAACACTGCCGAC
AGCAATAGCTTGGTCTTGGTCGATGAGCTTGGGGCTGGTACCGACCCTCAGGAAGGGGCTAGTCTAGCCATGGCAATCCT
AGAGCACCTCCGTTTGAGCCAGATTAAGACCATGGCTACTACTCACTATCCTGAGCTTAAGGCCTATGGGATTGAGACAC
AACATGTGGAAAATGCTAGCATGGAGTTTGACACAGCAACTCTAAGACCTACCTATCGCTTTATGCAAGGGGTTCCTGGT
CGCTCTAACGCCTTTGAGATTGCTCGTCGCCTCGGTTTGAATGAGATTATTGTCAAGGAAGCAGAAAACCTCACTGATAC
GGATAGTGATGTCAACCGTATCATCGAGCAACTTGAAGCCCAAACTGTAGAAACACAAAAACGTCTGGAGCACATCAAGG
ACGTTGAGCAAGAGAACCTTAAATTCAACCGTGCGGTCAAGAAACTCTATAATGAATTCTCCCATGAGTACGACAAGGAA
CTCGAAAAGGCTCAAAAAGAAATTCAAGAGATGGTGGATACAGCTTTAGCTGAAAGCGATAGTATTCTCAAAAATCTCCA
TGATAAGAGTCAACTCAAGCCTCATGAAGTTATCGACGCCAAAGGGAAACTTAAGAAACTTGCCGCACAAGTCGACCTTT
CTAAGAACAAGGTTCTTCGTAAAGCCAAGAAAGAAAAGGCTACGCGTGCCCCTCGTGTCGGTGATGATATCATCGTTACT
GCCTATGGGCAACGTGGTACGCTCACCAGTCAAGCCAAAAATGGTAACTGGGAAGCTCAAGTGGGTCTCATCAAGATGAG
CCTAAAGGCAGACGAATTCACTCTGGTTCGTACCCAAGCAGAAGCACAACAACCCAAGAAAAAACAAATTAATGTGGTTA
AAAAAGCCAAGAAGACATCTTCTGATGGGCCTCGTGCCCGTCTAGACCTTCGTGGGAAACGTTACGAAGAAGCCATGCAA
GAGCTCGATGCCTTTATTGACCAAGCTCTACTTAACAACATGAGTCAGGTGGAAATCATTCACGGTATTGGTACCGGTGT
CATCCGAGATGCTGTAACCAAATATCTCCGCCGTCATCGCCATGTTAAAAATTTTGAATATGCCCCACAAAGTGCTGGTG
GTTCCGGATGTACCATCGCAACCTTGGGTTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(708-782)

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-672)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.295

100

0.398