Detailed information NTG1010177

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1X08_RS04475
• Genome accession: NZ_LR822025
• Coordinates: 881003..881884 (+)
• Length: 293 a.a.
• NCBI ID: WP_084828863.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_961
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 876003..886884

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X08_RS04450 (STHERMO_0994)	-	877505..877960 (+)	456	WP_180482600.1	DUF4832 domain-containing protein	-
H1X08_RS04455 (STHERMO_0995)	galE	877975..878988 (+)	1014	WP_180482601.1	UDP-glucose 4-epimerase GalE	-
H1X08_RS04460 (STHERMO_0996)	-	879176..879412 (+)	237	WP_002946959.1	DUF1146 family protein	-
H1X08_RS04465 (STHERMO_0997)	murA	879480..880751 (+)	1272	WP_180482602.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1X08_RS04470 (STHERMO_0998)	-	880753..880941 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1X08_RS04475 (STHERMO_0999)	endA	881003..881884 (+)	882	WP_084828863.1	DNA/RNA non-specific endonuclease	Machinery gene
H1X08_RS10675 (STHERMO_1001)	-	882059..883316 (+)	1258	Protein_851	ISL3 family transposase	-
H1X08_RS04490	-	883445..883972 (-)	528	WP_179971942.1	HdeD family acid-resistance protein	-
H1X08_RS11375	-	884025..884183 (-)	159	WP_179973363.1	hypothetical protein	-
H1X08_RS04500 (STHERMO_1005)	-	884226..884702 (+)	477	WP_179971941.1	transposase	-
H1X08_RS04505 (STHERMO_1007)	-	884834..886090 (+)	1257	Protein_855	ISL3 family transposase	-
H1X08_RS04510 (STHERMO_1009)	-	886154..886804 (-)	651	WP_179971939.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31768.48 Da
• Isoelectric Point: 10.0031

>NTDB_id=1010177 H1X08_RS04475 WP_084828863.1 881003..881884(+) (endA) [Streptococcus thermophilus isolate STH_CIRM_961]
MAKGKTSLTNKQKRQFVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNYLTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDNSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1010177 H1X08_RS04475 WP_084828863.1 881003..881884(+) (endA) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGGCAAAAGGAAAAACATCTTTGACAAATAAACAGAAACGTCAGTTCGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGCAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGAAAAT
CTAATAAATCCATTAAATCTAATTATTTAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGAGCCTATATTATTAATGGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCTTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAATTCTACAGGTCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCTTGATTTATGAAGGAGAGAACCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGATC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATAACCCTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (98-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	75.893	76.451	0.58
endA	Streptococcus pneumoniae D39	75.893	76.451	0.58
endA	Streptococcus pneumoniae R6	75.893	76.451	0.58
endA	Streptococcus pneumoniae TIGR4	75.893	76.451	0.58