Detailed information NTG1010099

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: H0513_RS08290
• Genome accession: NZ_LR822023
• Coordinates: 1579306..1580091 (-)
• Length: 261 a.a.
• NCBI ID: WP_179972215.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_368
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1574306..1585091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0513_RS08255 (STHERMO_1849)	gatC	1574754..1575056 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
H0513_RS08260 (STHERMO_1850)	-	1575197..1575403 (-)	207	WP_232087148.1	glycosyltransferase	-
H0513_RS08265 (STHERMO_1851)	-	1575304..1575675 (-)	372	WP_332068334.1	glycosyltransferase	-
H0513_RS08270	-	1575991..1577004 (-)	1014	Protein_1560	family 1 glycosylhydrolase	-
H0513_RS08275 (STHERMO_1856)	msrA	1577192..1577701 (-)	510	WP_002951714.1	peptide-methionine (S)-S-oxide reductase MsrA	-
H0513_RS08280 (STHERMO_1857)	-	1577713..1578561 (-)	849	WP_179973029.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
H0513_RS08285 (STHERMO_1858)	-	1578686..1579243 (-)	558	WP_179972214.1	cysteine hydrolase family protein	-
H0513_RS08290 (STHERMO_1859)	codY	1579306..1580091 (-)	786	WP_179972215.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
H0513_RS08295 (STHERMO_1860)	-	1580350..1581564 (-)	1215	WP_179972216.1	pyridoxal phosphate-dependent aminotransferase	-
H0513_RS08300 (STHERMO_1861)	-	1581919..1582371 (+)	453	WP_002946987.1	universal stress protein	-
H0513_RS11155	-	1582551..1583120 (+)	570	Protein_1567	IS30 family transposase	-
H0513_RS08305 (STHERMO_1865)	-	1583192..1583945 (-)	754	Protein_1568	hypothetical protein	-
H0513_RS08310 (STHERMO_1867)	pflA	1584014..1584814 (-)	801	WP_179972217.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28928.00 Da
• Isoelectric Point: 4.4150

>NTDB_id=1010099 H0513_RS08290 WP_179972215.1 1579306..1580091(-) (codY) [Streptococcus thermophilus isolate STH_CIRM_368]
MANLLDKTRKITSILQRSVDNLEGDLPYNNMAAQLADIIDCNAAIVNGGGTLLGYAMKYKTNNDRVEEFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVESKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIAATVVGLQLLN
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=1010099 H0513_RS08290 WP_179972215.1 1579306..1580091(-) (codY) [Streptococcus thermophilus isolate STH_CIRM_368]
ATGGCAAATTTGCTTGATAAAACACGCAAAATTACTTCTATCTTGCAACGCTCAGTAGATAATTTGGAAGGAGATCTTCC
ATATAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATCGTAAATGGTGGAGGTACTCTCCTTG
GTTATGCTATGAAATACAAAACCAACAATGACCGTGTGGAAGAGTTTTTTAAAGCGAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATCAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCAGCTACAGTAGTTGGTTTGCAATTGTTGAAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATCACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGATAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

• CodY GAF-like domain (CodY) (3-182)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	65.759	98.467	0.648
codY	Bacillus subtilis subsp. subtilis str. 168	53.441	94.636	0.506