Detailed information NTG1009966

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H0514_RS04475
• Genome accession: NZ_LR822020
• Coordinates: 880164..881045 (+)
• Length: 293 a.a.
• NCBI ID: WP_084828863.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 875164..886045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS04450 (STHERMO_1002)	-	875710..877119 (+)	1410	WP_415669551.1	DUF4832 domain-containing protein	-
H0514_RS04455 (STHERMO_1003)	galE	877134..878147 (+)	1014	WP_179973336.1	UDP-glucose 4-epimerase GalE	-
H0514_RS04460 (STHERMO_1004)	-	878335..878571 (+)	237	WP_002946959.1	DUF1146 family protein	-
H0514_RS04465 (STHERMO_1005)	murA	878641..879912 (+)	1272	WP_179971943.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0514_RS04470 (STHERMO_1006)	-	879914..880102 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H0514_RS04475 (STHERMO_1007)	endA	880164..881045 (+)	882	WP_084828863.1	DNA/RNA non-specific endonuclease	Machinery gene
H0514_RS10650 (STHERMO_1008)	-	881220..882477 (+)	1258	Protein_838	ISL3 family transposase	-
H0514_RS04490	-	882606..883133 (-)	528	WP_179971942.1	HdeD family acid-resistance protein	-
H0514_RS11230	-	883186..883344 (-)	159	WP_179973363.1	hypothetical protein	-
H0514_RS04500 (STHERMO_1012)	-	883387..883863 (+)	477	WP_179971941.1	transposase	-
H0514_RS04505 (STHERMO_1013)	-	883995..885252 (+)	1258	WP_179971940.1	ISL3 family transposase	-
H0514_RS04510 (STHERMO_1016)	-	885316..885966 (-)	651	WP_179971939.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31768.48 Da
• Isoelectric Point: 10.0031

>NTDB_id=1009966 H0514_RS04475 WP_084828863.1 880164..881045(+) (endA) [Streptococcus thermophilus isolate STH_CIRM_956]
MAKGKTSLTNKQKRQFVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNYLTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDNSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1009966 H0514_RS04475 WP_084828863.1 880164..881045(+) (endA) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGGCAAAAGGAAAAACATCTTTGACAAATAAACAGAAACGTCAGTTCGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGCAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGAAAAT
CTAATAAATCCATTAAATCTAATTATTTAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGAGCCTATATTATTAATGGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCTTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAATTCTACAGGTCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCTTGATTTATGAAGGAGAGAACCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGATC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATAACCCTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (98-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	75.893	76.451	0.58
endA	Streptococcus pneumoniae D39	75.893	76.451	0.58
endA	Streptococcus pneumoniae R6	75.893	76.451	0.58
endA	Streptococcus pneumoniae TIGR4	75.893	76.451	0.58