Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H0514_RS00850 Genome accession   NZ_LR822020
Coordinates   149788..150081 (+) Length   97 a.a.
NCBI ID   WP_179972344.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 144788..155081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS00825 (STHERMO_0166) - 146739..147101 (+) 363 WP_179972348.1 DUF1033 family protein -
  H0514_RS00830 (STHERMO_0167) comGA/cglA/cilD 147182..148123 (+) 942 WP_179972347.1 competence type IV pilus ATPase ComGA Machinery gene
  H0514_RS00835 (STHERMO_0168) comGB 148005..149105 (+) 1101 WP_179973355.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0514_RS00840 (STHERMO_0169) comGC 149102..149428 (+) 327 WP_179972346.1 competence type IV pilus major pilin ComGC Machinery gene
  H0514_RS00845 (STHERMO_0170) comGD 149388..149816 (+) 429 WP_269473123.1 competence type IV pilus minor pilin ComGD Machinery gene
  H0514_RS00850 (STHERMO_0171) comGE 149788..150081 (+) 294 WP_179972344.1 competence type IV pilus minor pilin ComGE Machinery gene
  H0514_RS00855 (STHERMO_0172) comGF 150065..150502 (+) 438 WP_179972343.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0514_RS00860 (STHERMO_0173) comGG 150480..150791 (+) 312 WP_179972342.1 competence type IV pilus minor pilin ComGG Machinery gene
  H0514_RS00865 (STHERMO_0174) comGH 150842..151798 (+) 957 WP_179972341.1 class I SAM-dependent methyltransferase Machinery gene
  H0514_RS00870 (STHERMO_0175) - 151854..153047 (+) 1194 WP_179972340.1 acetate kinase -
  H0514_RS00875 (STHERMO_0176) - 153295..153492 (+) 198 WP_179972339.1 helix-turn-helix transcriptional regulator -
  H0514_RS11190 (STHERMO_0177) - 153504..153945 (+) 442 Protein_129 CAAX protease -
  H0514_RS00880 (STHERMO_0178) - 154042..154704 (+) 663 WP_179972338.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10830.71 Da        Isoelectric Point: 10.4561

>NTDB_id=1009922 H0514_RS00850 WP_179972344.1 149788..150081(+) (comGE) [Streptococcus thermophilus isolate STH_CIRM_956]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQDVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1009922 H0514_RS00850 WP_179972344.1 149788..150081(+) (comGE) [Streptococcus thermophilus isolate STH_CIRM_956]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGATATATTCTTATTGAAAGCCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGATGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTAAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

42.268

100

0.423
  comGE Streptococcus mutans UA159

42.268

100

0.423