Detailed information NTG1009902

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q6165_RS09655
• Genome accession: NZ_CP158131
• Coordinates: 1967999..1969042 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN51
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1962999..1974042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q6165_RS09625 (Q6165_09615)	-	1963420..1964676 (-)	1257	WP_001795108.1	aminopeptidase	-
Q6165_RS09630 (Q6165_09620)	-	1964679..1964879 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q6165_RS09635 (Q6165_09625)	-	1965026..1965490 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q6165_RS09640 (Q6165_09630)	-	1965497..1965772 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q6165_RS09645 (Q6165_09635)	-	1966050..1967267 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q6165_RS09650 (Q6165_09640)	vraR	1967380..1968009 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q6165_RS09655 (Q6165_09645)	vraS	1967999..1969042 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q6165_RS09660 (Q6165_09650)	liaF	1969039..1969740 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q6165_RS09665 (Q6165_09655)	-	1969755..1970141 (-)	387	WP_001110179.1	hypothetical protein	-
Q6165_RS09670 (Q6165_09660)	map	1970358..1971116 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q6165_RS09675 (Q6165_09665)	-	1971647..1972633 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
Q6165_RS09680 (Q6165_09670)	-	1973064..1973477 (-)	414	WP_001557448.1	hypothetical protein	-
Q6165_RS09685 (Q6165_09675)	-	1973506..1973616 (-)	111	WP_112386585.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1009902 Q6165_RS09655 WP_001017131.1 1967999..1969042(-) (vraS) [Staphylococcus aureus strain BSN51]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1009902 Q6165_RS09655 WP_001017131.1 1967999..1969042(-) (vraS) [Staphylococcus aureus strain BSN51]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1